Evidence map›Paper›PMID 33743746›Full record

ArticleHealth and quality of life outcomes2021

Content validity of preference-based measures for economic evaluation in chronic obstructive pulmonary disease.

Ava Mehdipour, Sachi O'Hoski, Marla K Beauchamp, Joshua Wald, Ayse Kuspinar

Abstract readMulticenter StudyValidation Study
In one paragraph

Article in Health and quality of life outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ava MehdipourSchool of Rehabilitation Science, McMaster University, 1400 Main St. W. Room 435, IAHS, Hamilton, ON, L8S 1C7, Canada.
Sachi O'HoskiSchool of Rehabilitation Science, McMaster University, 1400 Main St. W. Room 435, IAHS, Hamilton, ON, L8S 1C7, Canada.
Marla K BeauchampSchool of Rehabilitation Science, McMaster University, 1400 Main St. W. Room 435, IAHS, Hamilton, ON, L8S 1C7, Canada.
Joshua WaldFirestone Institute for Respiratory Health, 50 Charlton Ave E, Hamilton, ON, L8N 4A6, Canada.
Ayse KuspinarSchool of Rehabilitation Science, McMaster University, 1400 Main St. W. Room 435, IAHS, Hamilton, ON, L8S 1C7, Canada. kuspinaa@mcmaster.ca.ORCID http://orcid.org/0000-0002-3886-0407

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGeneric preference-based measures (GPBMs) are health-related quality of life (HRQoL) measures commonly used to evaluate the cost-utility of interventions in healthcare. However, the degree to which the content of GPBMs reflect the HRQoL of individuals with chronic obstructive pulmonary disease (COPD) has not yet been assessed. The purpose of this study was to examine the content and convergent validity of GPBMs in people with COPD.

methodsCOPD patients were recruited from healthcare centers in Ontario, Canada. The Patient-Generated Index (PGI) (an individualized HRQoL measure) and the RAND-36 (to obtain SF-6D scores; a GPBM) were administered. Life areas nominated with the PGI were coded using the International Classification of Functioning Disability and Health and mapped onto GPBMs.

resultsWe included 60 participants with a mean age of 70 and FEV1% predicted of 43. The mean PGI score was 34.55/100 and the top three overarching areas that emerged were: 'mobility' (25.93%), 'recreation and leisure' (25.19%) and 'domestic life' (19.26%). Mapping of the nominated areas revealed that the Quality of Well-Being scale covered the highest number of areas (84.62%), Health Utilities Indices covered the least (15.38% and 30.77%) and other GPBMs covered between 46 and 62%. A correlation of 0.32 was calculated between the SF-6D and the PGI.

conclusionsThe majority of GPBMs covered approximately half of the areas reported as being important to individuals with COPD. When areas relevant to COPD are not captured, HRQoL scores generated by these measures may inaccurately reflect patients' values and affect cost-effectiveness decisions.

Indexed as

Quality of LifeAgedCost-Benefit AnalysisFemaleHumansMaleMiddle AgedOntarioPatient PreferencePulmonary Disease, Chronic ObstructiveSurveys and QuestionnairesContent validityCOPDHRQoLPreference-based measures

Identifiers

PMID33743746
PMCPMC7981836

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.