ArticleBMC complementary medicine and therapies2021
Extracts of endophytic fungi from leaves of selected Nigerian ethnomedicinal plants exhibited antioxidant activity.
Article in BMC complementary medicine and therapies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 74 citations in OpenAlex.
- Endophytic Fungal Metabolites as Modulators of Key Signaling Pathways in Chronic Diseases and Aging.Antibiotics (Basel, Switzerland) · 2026Review
- Computational prediction and docking studies of bioactive metabolites from grass-derived endophytic fungi.Archives of microbiology · 2026Article
- Untapped microbial factories for next-generation therapeutics: Endophytic fungi of medicinal plants.Microbial cell factories · 2026Review
- The GenusMolecules (Basel, Switzerland) · 2026Review
- Endophyte-mediated biosynthesis of biogenic nanoparticles: mechanisms and biomedical applications.Archives of microbiology · 2026Review
- A fungal endophyte of the medicinal plant,Frontiers in microbiology · 2026Article
- Diversity, bioactivities, and metabolomics of culturable endophytic fungi from the medicinal plantFrontiers in microbiology · 2026Article
- Endophytic Fungal Diversity and Its Interaction Mechanism with Medicinal Plants.Molecules (Basel, Switzerland) · 2025Review
- Article
- In Vitro and In Vivo Antitumor Activity ofMicroorganisms · 2024Article
- In vitro antiplasmodial and anticancer analyses of endophytic fungal extracts isolated from selected Nigerian medicinal plants.Scientific reports · 2024Article
- Antioxidant properties and L-asparaginase activities of endophytic fungi from Cymbidium orchids.Folia microbiologica · 2024Article
- Phytochemical characterization ofHeliyon · 2024Article
- Optimisation of indole acetic acid production by Neopestalotiopsis aotearoa endophyte isolated from Thymus vulgaris and its impact on seed germination of Ocimum basilicum.BMC biotechnology · 2024Article
- Review
- Endophytes: a uniquely tailored source of potential antibiotic adjuvants.Archives of microbiology · 2024Review
- Diversity, molecular phylogenetics, and antibiotic biosynthetic potential of endophytic Actinobacteria isolated from medicinal plants in Nigeria.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Endophytic fungi ofSaudi journal of biological sciences · 2024Article
- Why Are There So Few Basidiomycota and Basal Fungi as Endophytes? A Review.Journal of fungi (Basel, Switzerland) · 2024Review
- Antibacterial and anticancer potential of bioactive compounds and secondary metabolites of endophytic fungi isolated fromFrontiers in microbiology · 2024Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlants with an ethnobotanical history are known to harbor diverse group of endophytic fungi, which constitute major natural sources of bioactive compounds. In the present study, we evaluated the antioxidant activity of endophytic fungi from eight Nigerian ethnomedicinal plants. Endophytic fungi were isolated from the leaves of Acalypha ornata, Albizia zygia, Alchornea cordifolia, Chrysophyllum albidum, Ficus exasperata, Gomphrena celosioides, Millettia thonningii, and Newbouldia laevis.
methodsEndophytic fungi were isolated from the leaves of selected plants via surface sterilization. Isolated fungi were identified by internal transcribed spacer (ITS-rDNA) sequence analysis. Pure fungal strains were subjected to fermentation process on solid rice medium and metabolites extracted using ethyl-acetate. Fungal crude extracts were screened for antioxidant activity using 2, 2- diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and reduction of ferric ion assays. Gas chromatography/mass spectrometry (GC/MS) analysis was used to identify the major chemical constituents in active fungal extracts.
resultsA total of eighteen fungal endophytes with fungal codes CU (061 and 062); ZA (161, 162, 163, and 164); LO (261); CA (041, 042, and 043); FE (081, 082, and 084); GE (091); MO (211 and 212); and NA (021 and 022) were isolated from the eight ethnomedicinal plants A. ornata, A. zygia, A. cordifolia, C. albidum, F. exasperata, G. celosioides, M. thonningii, and N. laevis respectively. ZA 163 and MO 211 fungal extracts showed significant (p < 0.05) radical scavenging activity with IC
conclusionThese results showed that leaves of the selected Nigerian plants harbor diverse group of endophytic fungi, which can be potential antioxidant resource.
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