Evidence map›Paper›PMID 33743682›Full record

ReviewMicrobial cell factories2021

Insights into the structure of Escherichia coli outer membrane as the target for engineering microbial cell factories.

Jianli Wang, Wenjian Ma, Xiaoyuan Wang

Open access · goldAbstract readReview
In one paragraph

Review in Microbial cell factories, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 100 citations in OpenAlex.

  1. Streptavidin-DisplayingSensors (Basel, Switzerland) · 2026
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  16. Restoring Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2024
    Article
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  18. Engineered Cell Elongation Promotes Extracellular Electron Transfer of Shewanella Oneidensis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jianli Wang *State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China.
Wenjian Ma *State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China.
Xiaoyuan WangState Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China. xwang@jiangnan.edu.cn.ORCID http://orcid.org/0000-0001-5186-8668
Jiangnan University · CN

Funding

National Natural Science Foundation of China 32000020Natural Science Foundation of Jiangsu Province BK20200615the National Key R&D Program of China 2018YFA0900300
6 · The paper itself

Abstract

Escherichia coli is generally used as model bacteria to define microbial cell factories for many products and to investigate regulation mechanisms. E. coli exhibits phospholipids, lipopolysaccharides, colanic acid, flagella and type I fimbriae on the outer membrane which is a self-protective barrier and closely related to cellular morphology, growth, phenotypes and stress adaptation. However, these outer membrane associated molecules could also lead to potential contamination and insecurity for fermentation products and consume lots of nutrients and energy sources. Therefore, understanding critical insights of these membrane associated molecules is necessary for building better microbial producers. Here the biosynthesis, function, influences, and current membrane engineering applications of these outer membrane associated molecules were reviewed from the perspective of synthetic biology, and the potential and effective engineering strategies on the outer membrane to improve fermentation features for microbial cell factories were suggested.

Indexed as

Bacterial Outer MembraneCell EngineeringEscherichia coliEscherichia coli ProteinsFermentationSynthetic BiologyEscherichia coli ProteinsEscherichia coliExopolysaccharideFimbriaFlagellaInclusion bodiesLipopolysaccharideMembrane engineeringMicrobial cell factoriesOuter membranePoly-3-hydroxybutyrate

Identifiers

PMID33743682
PMCPMC7980664
OpenAlexW3137080761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.