ArticleBMC gastroenterology2021
Study on the relationship of depression, anxiety, lifestyle and eating habits with the severity of reflux esophagitis.
Article in BMC gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Gastrointestinal Issues in Depression, Anxiety, and Neurodegenerative Diseases: A Systematic Review on Pathways and Clinical Targets Implications.CNS & neurological disorders drug targets · 2024Pooled it
- Mendelian randomization study of gastroesophageal reflux disease and major depression.PloS one · 2023Pooled it
- Relationships Among Type D Personality, Symptoms, Depression and Anxiety, and Quality of Life in Patients With Gastroesophageal Reflux Disease.The journal of nursing research : JNR · 2026Article
- Identification of salivary lipid biomarkers for noninvasive diagnosis of reflux esophagitis via UHPLC-MS-based lipidomics.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Healthcare burden of treated gastroesophageal reflux disease among U.S. adults, 2018-2023: a pooled cross-sectional analysis of the medical expenditure panel survey.Frontiers in medicine · 2026Article
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- Article
- Predicting depression risk in middle-aged and elderly adults in China using CNN-BiLSTM-Attention mechanism and LSTM+SHAP framework.BMC psychiatry · 2025Article
- Integrating AI with Advanced Hyperspectral Imaging for Enhanced Classification of Selected Gastrointestinal Diseases.Bioengineering (Basel, Switzerland) · 2025Article
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- Analyzing the correlation between gastroesophageal reflux disease and anxiety and depression based on ordered logistic regression.Scientific reports · 2024Article
- The status quo of short video as sources of health information on gastroesophageal reflux disease in China: a cross-sectional study.Frontiers in public health · 2024Article
- Depressive symptoms and all-cause mortality among middle-aged and older people in China and associations with chronic diseases.Frontiers in public health · 2024Article
- Association of depression with gastroesophageal reflux disease, and the mediating role of risk factors: a Mendelian randomization study.Frontiers in psychiatry · 2024Article
- Depression Promotes Gastroesophageal Reflux Disease: New Evidence Based on Mendelian Randomization.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Major depressive disorders in patients with inflammatory bowel disease and rheumatoid arthritis.World journal of clinical cases · 2023Article
- Association of educational attainment with esophageal cancer, Barrett's esophagus, and gastroesophageal reflux disease, and the mediating role of modifiable risk factors: A Mendelian randomization study.Frontiers in public health · 2023Article
- Article
- Lifestyle Factors Associated With Erosive Esophagitis in Japanese Individuals With and Without Obesity Undergoing Health Checkups.Journal of primary care & community healthArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe etiology of reflux esophagitis (RE) is multi-factorial. This study analyzed the relationship of depression, anxiety, lifestyle and eating habits with RE and its severity and further explored the impact of anxiety and depression on patients' symptoms and quality of life.
methodsFrom September 2016 to February 2018, a total of 689 subjects at Xuanwu Hospital Capital Medical University participated in this survey. They were divided into the RE group (patients diagnosed with RE on gastroscopy, n = 361) and the control group (healthy individuals without heartburn, regurgitation and other gastrointestinal symptoms, n = 328). The survey included general demographic information, lifestyle habits, eating habits, comorbidities, current medications, the gastroesophageal reflux disease (GERD) questionnaire (GerdQ), the Patient Health Questionnaire-9 depression scale and the General Anxiety Disorder-7 anxiety scale.
resultsThe mean age and sex ratio of the two groups were similar. Multivariate logistic regression analysis identified the following factors as related to the onset of RE (p < 0.05): low education level; drinking strong tea; preferences for sweets, noodles and acidic foods; sleeping on a low pillow; overeating; a short interval between dinner and sleep; anxiety; depression; constipation; history of hypertension; and use of oral calcium channel blockers. Ordinal logistic regression analysis revealed a positive correlation between sleeping on a low pillow and RE severity (p = 0.025). Depression had a positive correlation with the severity of symptoms (r
conclusionsMany lifestyle factors and eating habits were correlated with the onset of RE. Notably, sleeping on a low pillow was positively correlated with RE severity, and depression was positively related to the severity of symptoms and patients' quality of life.
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