Evidence map›Paper›PMID 33743418›Full record

ArticleChemosphere2021

Trends in urinary metabolites of polycyclic aromatic hydrocarbons (PAHs) in the non-smoking U.S. population, NHANES 2001-2014.

Barbara Hudson-Hanley, Ellen Smit, Adam Branscum, Perry Hystad, Molly L Kile

Open access · greenAbstract read
In one paragraph

Article in Chemosphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Barbara Hudson-HanleyOregon State University, College of Public Health & Human Sciences, Environmental & Occupational Health Program, Corvallis, OR, USA. Electronic address: barbara.hanley@lifetime.oregonstate.edu.
Ellen SmitOregon State University, College of Public Health & Human Sciences, Epidemiology Program, Corvallis, OR, USA.
Adam BranscumOregon State University, College of Public Health & Human Sciences, Biostatistics Program, Corvallis, OR, USA.
Perry HystadOregon State University, College of Public Health & Human Sciences, Environmental & Occupational Health Program, Corvallis, OR, USA.
Molly L KileOregon State University, College of Public Health & Human Sciences, Environmental & Occupational Health Program, Corvallis, OR, USA.
Oregon State University · US

Funding

Research Experience and Training Coordination CoreP42ES016465 · NIEHS · OREGON STATE UNIVERSITY · PI Susan C Tilton · 2009 to 2026
$52.5M
NIEHS NIH HHS P42 ES016465
6 · The paper itself

Abstract

backgroundRecent studies indicate airborne PAH levels have decreased in the U.S., but it is unclear if this has resulted in PAH exposure changes in the U.S. POPULATION:

objectiveExamine temporal trends in urinary metabolites of Naphthalene, Fluorene, Phenanthrene, and Pyrene in U.S. non-smokers, 6+ years old.

methodsWe used biomonitoring data from the National Health and Nutrition Examination Survey (NHANES) program, 2001-2014, (N = 11,053) using survey weighted linear regression. Models were adjusted for age, sex, race/ethnicity, creatinine, BMI, income, diet, and seasonality. Stratified models evaluated the effect of age, sex, and race/ethnicity on trends.

resultsBetween 2001 and 2014, Naphthalene exposure increased 36% (p < 0.01); Pyrene exposure increased 106% (p < 0.01); Fluorene and Phenanthrene exposure decreased 55% (p < 0.01), and 37% (p < 0.01), respectively. Naphthalene was the most abundant urinary PAH, 20-fold higher than Fluorene and Phenanthrene, and over 50-fold higher than Pyrene compared to reference groups, effect modification was observed by age (Naphthalene, Pyrene), sex (Fluorene, Pyrene), and race/ethnicity (Naphthalene, Fluorene, Phenanthrene, Pyrene). SIGNIFICANCE: This study shows exposure to Naphthalene and Pyrene increased, while exposure to Fluorene and Phenanthrene decreased among the non-smoking U.S. general population between 2001 and 2014, suggesting environmental sources of PAHs have changed over the time period.

Indexed as

Polycyclic Aromatic HydrocarbonsBiological MonitoringBiomarkersChildCreatinineDietEnvironmental MonitoringHumansNutrition SurveysBiomarkersCreatininePolycyclic Aromatic HydrocarbonsAir pollutionHuman biomonitoringNaphthaleneNHANESPAHsPyrene

Identifiers

PMID33743418
PMCPMC8172479
OpenAlexW3134177674

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.