SynthesisEpilepsy & behavior : E&B2021
Status epilepticus and COVID-19: A systematic review.
Synthesis in Epilepsy & behavior : E&B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Epilepsy and the risk of severe coronavirus disease 2019 outcomes: A systematic review, meta-analysis, and meta-regression.Epilepsy & behavior : E&B · 2021Pooled it
- Epidemiology of Status Epilepticus in Kazakhstan: A 10-Year Population-Based Study.Journal of clinical medicine · 2025Article
- The Impact of Comorbidities, EEG Abnormalities, and ASM Use as a Predicting Outcomes in Pediatric Status Epilepticus.Neuropsychiatric disease and treatment · 2025Article
- Article
- Status Epilepticus with Unilateral Brain Edema in COVID-19.Internal medicine (Tokyo, Japan) · 2024Article
- Clinical outcomes of patients with seizure admitted for COVID-19: Findings from the Philippine CORONA study.Heliyon · 2024Article
- Seizures in febrile children with SARS-CoV-2 infection: clinical features, short-term follow-up.BMC pediatrics · 2024Article
- COVID-19 vaccinations for patients with epilepsy in Guizhou Province, China: A cross-sectional study.Heliyon · 2024Article
- Outcomes in Patients With COVID-19 With Acute Encephalopathy and Coma: An International Prospective Study.Neurology · 2023Observational
- Review
- Non-1st seizure was less severe than 1st seizure with non-urgent level among suspected seizures transferred by ambulance.PloS one · 2023Article
- Seizures, Vitamin D Deficiency, and Severe Hypophosphatemia: The Unique Presentation of a SARS-CoV-2 Case.Cureus · 2023Article
- Neurological and Neuroradiological Patterns with COVID-19 Infection in Children: A Single Institutional Study.The Indian journal of radiology & imaging · 2022Article
- Potential risk of liver injury in epileptic patients during COVID-19 pandemic.World journal of virology · 2022Review
- Case 34-2022: A 57-Year-Old Woman with Covid-19 and Delusions.The New England journal of medicine · 2022Article
- Treatment of COVID-19-induced refractory status epilepticus by tocilizumab.European journal of neurology · 2022Article
- COVID-19 vaccine in patients with Dravet syndrome: Observations and real-world experiences.Epilepsia · 2022Article
- Review
- Neurological Manifestations in Pediatric Patients Hospitalized for COVID-19: Experiences of the National Medical Center "20 de Noviembre" in Mexico City.Children (Basel, Switzerland) · 2022Article
- COVID-19 pandemic influence on epilepsy course in pediatric patients.Epilepsy & behavior : E&B · 2022Article
Corrections and comments
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Authors and funding
16 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn March 2020, the World Health Organization declared the SARS-CoV-2 infection-related coronavirus Disease (COVID-19) a pandemic. During the first and second waves of the pandemic spread, there have been several reports of COVID-19-associated neurological manifestations, including acute seizures and status epilepticus (SE). In this systematic review, we summarized the available data on clinical features, diagnosis, and therapy of COVID-19-related SE.
methodsWe performed a systematic search of the literature to identify data on demographics, clinical, neurophysiological, and neuroradiological data of patients with COVID-19-related SE. We used regression models (linear or logistic) with a stepwise forward method to identify features associated with mortality or severity of SE.
resultsThirty-nine articles were included with a total of 47 cases of SE associated with COVID-19. Age, time between the acute respiratory phase of SARS-CoV-2 infection and SE onset, and hospitalization correlated with a higher SE severity as assessed by quantitative validated scales.
conclusionsSE can be a neurological manifestation of SARS-CoV-2 infection. Although a possible association between SE and COVID-19 has been reported, the exact mechanisms are still not fully understood. Systemic inflammatory syndrome due to cytokine release could play a role in COVID-19-related SE.
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Registered trials
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