Evidence map›Paper›PMID 33743081›Full record

ArticleActa diabetologica2021

The interaction between metabolic syndrome and physical activity, and risk for gestational diabetes mellitus.

Ashleigh K Schneider, Shalem Y Leemaqz, Julia Dalton, Petra E Verburg, Ben W Mol, Gus A Dekker, Claire T Roberts, Jessica A Grieger

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In one paragraph

Article in Acta diabetologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ashleigh K SchneiderRobinson Research Institute, University of Adelaide, North Adelaide, 5005, Australia.
Shalem Y LeemaqzRobinson Research Institute, University of Adelaide, North Adelaide, 5005, Australia.
Julia DaltonRobinson Research Institute, University of Adelaide, North Adelaide, 5005, Australia.
Petra E VerburgRobinson Research Institute, University of Adelaide, North Adelaide, 5005, Australia.
Ben W MolDepartment of Obstetrics and Gynaecology, Monash University, Clayton, 3168, Australia.
Gus A DekkerRobinson Research Institute, University of Adelaide, North Adelaide, 5005, Australia.
Claire T RobertsRobinson Research Institute, University of Adelaide, North Adelaide, 5005, Australia.
Jessica A GriegerRobinson Research Institute, University of Adelaide, North Adelaide, 5005, Australia. jessica.grieger@adelaide.edu.au.ORCID http://orcid.org/0000-0003-1515-948X
The University of Adelaide · AUFlinders University · AULyell McEwin Hospital · AUUniversity of Aberdeen · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsMetabolic syndrome (MetS) is a cluster of risk factors which increases risk of cardiometabolic diseases in the adult population and increases risk for pregnancy complications such as gestational diabetes mellitus (GDM). Epidemiological data indicate that moderate-to-high levels of physical activity reduces the risk for GDM. The study aims to determine whether the association between MetS and GDM is affected by physical activity.

methodsWe performed a prospective cohort study among 1373 pregnant nulliparous women in Adelaide, South Australia. At 9-16 weeks' gestation, demographic, lifestyle and self-reported frequencies of physical activity were obtained, and a non-fasting blood sample was taken for assessment of MetS, defined using the International Diabetes Federation criteria. GDM was diagnosed at 24-28 weeks' gestation using the World Health Organization classification.

results1158 pregnant women were included: 107 (9%) women had MetS in early pregnancy, and 184 (16%) developed GDM. Having MetS increased the risk of developing GDM (37.4% vs. 13.7%, adjusted RR 2.5; 95% CI 1.7, 3.6). The interaction effect (RR; (95% CI) between MetS and physical activity was not significant (vigorous physical activity: 2.60; 0.46, 14.71) for ≥ 4 times per week; less vigorous activity; 0.77; 0.15, 4.02 for ≥ 4 times per week; stair climbing ≥ once day (1.16; 0.54, 2.51), all compared to no physical activity).

conclusionsPhysical activity was not an effect modifier in the association between GDM and MetS. Information collected about the nature and extent of physical activity needs to be more detailed and granular to determine whether physical activity really has an effect.

Indexed as

AdultCohort StudiesDiabetes, GestationalExerciseFemaleHumansMetabolic SyndromePregnancyPregnancy ComplicationsProspective StudiesRisk FactorsSouth AustraliaYoung AdultExerciseGestational diabetes mellitusMetabolic syndromePhysical activityPregnancy

Identifiers

PMID33743081
OpenAlexW3136906299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.