ReviewPediatric radiology2021
Computed tomography in cystic fibrosis lung disease: a focus on radiation exposure.
Review in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Postural Influence on Ventilation Efficiency and Relationship With Oxygen-Enhanced MRI in Cystic Fibrosis.Pediatric pulmonology · 2026Article
- Structural and Functional Pulmonary MRI to Predict Pulmonary Exacerbations in Cystic Fibrosis.Chest · 2026Article
- [18F]FDG PET/MR to assess disease extension and inflammation in children and young adults with primary ciliary dyskinesia.European journal of nuclear medicine and molecular imaging · 2026Article
- Early structural lung changes in young children with cystic fibrosis: a call to action.Respiratory research & clinical practice · 2026Article
- A Question of Dose? Ultra-Low Dose Chest CT on Photon-Counting CT in People with Cystic Fibrosis.Tomography (Ann Arbor, Mich.) · 2025Article
- Ultralow dose computed tomography as an alternative to conventional chest radiography for the evaluation of disease severity in paediatric cystic fibrosis.Scientific reports · 2025Article
- Ultra-low dose computed tomography chestWorld journal of radiology · 2025Article
- A New Simple to Use Chest CT Scoring System: Validation Study.Pediatric pulmonology · 2025Article
- The impact of highly effective modulator therapy on sinusitis and dysosmia in young children with cystic fibrosis: a prospective study protocol.ERJ open research · 2025Article
- Low-dose high-resolution chest CT in adults with cystic fibrosis: intraindividual comparison between photon-counting and energy-integrating detector CT.European radiology experimental · 2024Article
- Paediatric Thoracic Imaging in Cystic Fibrosis in the Era of Cystic Fibrosis Transmembrane Conductance Regulator Modulation.Children (Basel, Switzerland) · 2024Review
- The occurrence and development of radiation-induced lung injury after interstitial brachytherapy and stereotactic radiotherapy in SD rats.Journal of inflammation (London, England) · 2023Article
- Implementation and evaluation of ultra-low dose CT in early cystic fibrosis lung disease.The European respiratory journal · 2023Article
- Pilot study to determine whether reduced-dose photon-counting detector chest computed tomography can reliably display Brody II score imaging findings for children with cystic fibrosis at radiation doses that approximate radiographs.Pediatric radiology · 2023Article
- Lung Ultrasound in the Evaluation of Lung Disease Severity in Children with Clinically Stable Cystic Fibrosis: A Prospective Cross-Sectional Study.Journal of clinical medicine · 2023Article
- Chest magnetic resonance imaging in cystic fibrosis: technique and clinical benefits.Pediatric radiology · 2023Review
- Perspectives on the translation of in-vitro studies to precision medicine in Cystic Fibrosis.EBioMedicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Thoracic computed tomography (CT) is the imaging reference method in the diagnosis, assessment and management of lung disease. In the setting of cystic fibrosis (CF), CT demonstrates increased sensitivity compared with pulmonary function tests and chest radiography, and findings correlate with clinical outcomes. Better understanding of the aetiology of CF lung disease indicates that even asymptomatic infants with CF can have irreversible pulmonary pathology. Surveillance and early diagnosis of lung disease in CF are important to preserve lung parenchyma and to optimise long-term outcomes. CF is associated with increased cumulative radiation exposure due to the requirement for repeated imaging from a young age. Radiation dose optimisation, important for the safe use of CT in children with CF, is best achieved in a team environment where paediatric radiologists work closely with paediatric respiratory physicians, physicists and radiography technicians to achieve the best patient outcomes. Despite the radiation doses incurred, CT remains a vital imaging tool in children with CF. Radiologists with special interests in CT dose optimisation and respiratory disease are key to the appropriate use of CT in paediatric imaging. Paediatric radiologists strive to minimise radiation dose to children whilst providing the best possible assessment of lung disease.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.