Evidence map›Paper›PMID 33742665›Full record

ArticleRheumatology (Oxford, England)2021

Epidemiology of biopsy-confirmed giant cell arteritis in southern Sweden-an update on incidence and first prevalence estimate.

Pavlos Stamatis, Aleksandra Turkiewicz, Martin Englund, Carl Turesson, Aladdin J Mohammad

Abstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. Temporal Artery Vascular Diseases.Journal of clinical medicine · 2022
    Review
  19. Global epidemiology of vasculitis.Nature reviews. Rheumatology · 2022
    Review
  20. Identification ofFrontiers in cardiovascular medicine · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Pavlos StamatisDepartment of Clinical Sciences Lund, Rheumatology, Lund University, Sweden.ORCID 0000-0003-1760-0734
Aleksandra TurkiewiczDepartment of Clinical Sciences Lund, Clinical Epidemiology Unit, Sweden.ORCID 0000-0003-1460-2275
Martin EnglundDepartment of Clinical Sciences Lund, Clinical Epidemiology Unit, Sweden.ORCID 0000-0003-3320-2437
Carl TuressonDepartment of Clinical Sciences Malmö, Rheumatology, Lund University, Sweden.ORCID 0000-0002-3805-2290
Aladdin J MohammadDepartment of Clinical Sciences Lund, Rheumatology, Lund University, Sweden.ORCID 0000-0002-7169-6936

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo characterize the epidemiology of temporal artery biopsy-positive (TAB+) GCA, including trends in incidence, seasonal variation and prevalence in Skåne, the southernmost region of Sweden.

methodsAll histopathology reports of TABs from 1997 through 2019 were reviewed to identify patients diagnosed with TAB+ GCA. Incidence rates based on the 23-year period and the point-prevalence at 31 December 2014 were determined. An alternative prevalence calculation included only TAB+ GCA patients living in the study area and receiving immunosuppressant therapy on the point-prevalence date.

resultsOne thousand three hundred and sixty patients were diagnosed with TAB+ GCA (71% female). The average annual incidence 1997-2019 was 13.3 (95% CI: 12.6, 14.0) per 100 000 inhabitants aged ≥50 years and was higher in females (17.8; 95% CI: 16.7, 18.9) than in males (8.2; 95% CI: 7.4, 9.0). The age- and sex-standardized incidence declined from 17.3 in 1997 to 8.7 in 2019, with incidence ratio (IR) of 0.98 per year (95% CI: 0.98, 0.99). A seasonal variation was observed with higher incidence during spring than winter [IR = 1.19 (95% CI: 1.03, 1.39)]. The overall point-prevalence of TAB+ GCA was 127.1/100 000 (95% CI: 117, 137.3) and was 75.5 (95% CI: 67.7, 83.3) when including only patients receiving immunosuppressants.

conclusionOver the past 2 decades, the incidence of biopsy-confirmed GCA has decreased by ∼2% per year. Still, a high prevalence of GCA on current treatment was observed. More cases are diagnosed during spring and summer than in the winter.

Indexed as

AgedBiopsyFemaleGiant Cell ArteritisHumansIncidenceMaleMiddle AgedPrevalenceSwedendemographicsglucocorticoidspopulation studiesregistryvasculitis

Identifiers

PMID33742665
PMCPMC8742826

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.