Evidence map›Paper›PMID 33742609›Full record

ArticleIndian pediatrics2021

Outcomes of Neonates Born to Mothers With Coronavirus Disease 2019 (COVID-19) - National Neonatology Forum (NNF) India COVID-19 Registry.

Kiran More, Deepak Chawla, Srinivas Murki, Baswaraj Tandur, Ashok K Deorari, Praveen Kumar, National Neonatology Forum (NNF) COVID-19 Registry Group

Open access · bronzeAbstract read
In one paragraph

Article in Indian pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 13 institutions in 1 country.

Kiran MoreSidra Medicine Hospital, Doha, Qatar.
Deepak ChawlaGovernment Medical College, Chandigarh.
Srinivas MurkiParamitha Children Hospital, Hyderabad, Telangana.
Baswaraj TandurPrincess Durru Shehvar Children's and General Hospital.
Ashok K DeorariAll India Institute of Medical Sciences, New Delhi.
Praveen KumarPostgraduate Institute of Medical Education and Research, Chandigarh. Correspondence to: Professor Praveen Kumar, Head, Division of Neonatology, Department of Pediatrics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. drpkumarpgi@gmail.com.
National Neonatology Forum (NNF) COVID-19 Registry Group
Gandhi Medical College & Hospital · INAll India Institute of Medical Sciences Bhubaneswar · INDeenanath Mangeshkar Hospital and Research Center · INKanchi Kamakoti CHILDS Trust Hospital · INPandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences · INMadras Medical College · INGovernment Medical College · INMedical College and Hospital, Kolkata · INNil Ratan Sircar Medical College and Hospital · INPost Graduate Institute of Medical Education and Research · INGovernment Medical College · INNRR Hospital · INRainbow Children's Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited evidence exists on perinatal transmission and outcomes of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in neonates.

objectiveTo describe clinical outcomes and risk factors for transmission in neonates born to mothers with perinatal SARS-CoV-2 infection.

designProspective cohort of suspected and confirmed SARS-CoV-2 infected neonates entered in National Neonatology Forum (NNF) of India registry. SUBJECTS: Neonates born to women with SARS-CoV-2 infection within two weeks before or two days after birth and neonates with SARS-CoV-2 infection. OUTCOMES: Incidence and risk factors of perinatal transmission.

resultsAmong 1713 neonates, SARS-CoV-2 infection status was available for 1330 intramural and 104 extramural neonates. SARS-CoV-2 positivity was reported in 144 intramural and 39 extramural neonates. Perinatal transmission occurred in 106 (8%) and horizontal transmission in 21 (1.5%) intramural neo-nates. Neonates roomed-in with mother had higher transmission risk (RR1.16, 95% CI 1.1 to 2.4; P=0.01). No association was noted with the mode of delivery or type of feeding. The majority of neonates positive for SARS-CoV2 were asymptomatic. Intra-mural SARS-CoV-2 positive neonates were more likely to be symptomatic (RR 5, 95%CI 3.3 to 7.7; P<0.0001) and need resuscitation (RR 2, 95%CI 1.0 to 3.9; P=0.05) compared to SARS-CoV-2 negative neonates. Amongst symptomatic neonates, most morbidities were related to prematurity and perinatal events.

conclusionsData from a large cohort suggests perinatal transmission of SARS-CoV-2 infection and increased morbidity in infected infants.

Indexed as

AdultCOVID-19COVID-19 TestingFemaleHumansIncidenceIndiaInfant, NewbornInfectious Disease Transmission, VerticalMothersNeonatal ScreeningNeonatologyPandemicsPregnancyPregnancy Complications, InfectiousProspective StudiesRNA, Viral

Identifiers

PMID33742609
PMCPMC8253678
OpenAlexW3165587687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.