SynthesisBrain and behavior2021
Associations between coronary heart disease and risk of cognitive impairment: A meta-analysis.
Synthesis in Brain and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Independent and Combined Effects of Obesity and Cardiovascular Diseases on the Risk of Cognitive Impairment and Dementia: A Systematic Review and Meta-Analysis of Prospective Cohort Studies Involving 8,276,914 Participants.International journal of molecular sciences · 2026Pooled it
- Associations between coronary heart disease and risk of cognitive impairment: A meta-analysis.Brain and behavior · 2021Pooled it
- Cognitive Decline in Chronic Coronary Syndrome: Associations with Vascular, Cardiac, and Neuropsychological Parameters.Medicina (Kaunas, Lithuania) · 2026Observational
- Machine learning-based predictive model for postoperative delirium of elderly patients with coronary heart disease undergoing non-cardiac surgery: a retrospective cohort study.Frontiers in psychiatry · 2026Article
- Cognitive impairment and risk of dementia in heart failure: the exuberating role of digoxin.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Retinal image-based deep learning for mild cognitive impairment detection in coronary artery disease population.Heart (British Cardiac Society) · 2025Article
- Inflammatory Status Modifies the Association Between Glycemic Traits and Cognitive Impairment in Patients With Coronary Artery Disease.Journal of the American Heart Association · 2025Article
- Role of Compensatory miRNA Networks in Cognitive Recovery from Heart Failure.Non-coding RNA · 2025Article
- Protecting vascular health: the role of flavonoids during pregnancy complications in mitigating the risk of vascular dementia later in life.Inflammopharmacology · 2025Review
- Attention as the primary cognitive domain affected in post-myocardial infarction cognitive impairment: a prospective multicenter study.Scientific reports · 2025Article
- Gender and Educational Trends in Lifetime Risk, Age at Onset, Expectancy, and Survival With Cardiovascular Disease in Finland, 1996-2020.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Associations of ischemic heart disease with brain glymphatic MRI indices and risk of Alzheimer's disease.The journal of prevention of Alzheimer's disease · 2025Article
- Association between ranolazine therapy and cognitive decline in elderly patients with ischemic heart disease.Frontiers in pharmacology · 2025Article
- Relationship Between Cognitive Ability and Phase Angle in Older Adults with Cardiovascular Disease: A Cross-Sectional Study.Clinical interventions in aging · 2025Article
- Association between life's essential 8 and cognitive impairment in older patients: results from NHANES 2011-2014.BMC geriatrics · 2024Article
- Inhibition of Extracellular Signal-Regulated Kinase Activity Improves Cognitive Function in Mice Subjected to Myocardial Infarction.Cardiovascular toxicology · 2024Article
- Review
- Association between triglyceride glucose-waist to height ratio and coronary heart disease: a population-based study.Lipids in health and disease · 2024Article
- Sleep duration, chronotype, health and lifestyle factors affect cognition: a UK Biobank cross-sectional study.BMJ public health · 2024Article
- Multimorbidity, cognitive phenotypes, and Alzheimer's disease plasma biomarkers in older adults: A population-based study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies have demonstrated that coronary heart disease (CHD) is a high risk factor for cognitive impairment, whereas other studies showed that there was no association between cognitive impairment and CHD. The relationship between CHD and cognitive impairment is still unclear based on these conflicting results. Thus, it is of importance to evaluate the association between CHD and cognitive impairment. The present study made a meta-analysis to explore the association between CHD and risk of cognitive impairment.
methodsArticles exploring the association between CHD and cognitive impairment and published before November 2020 were searched in the following databases: PubMed, Web of Science, Medline, EMBASE, and Google Scholar. We used STATA 12.0 software to compute the relative risks (RRs), odds ratios (ORs), or hazard ratios (HRs) and 95% confidence intervals (CIs).
resultsThe meta-analysis showed a positive association between CHD and risk of all-cause cognitive impairment with a random effects model (RR = 1.27, 95% CI 1.18 to 1.36, I
conclusionIn a word, CHD was significantly associated with an increased risk of developing cognitive impairment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.