Evidence map›Paper›PMID 33742433›Full record

ArticleSeminars in neurology2021

Brain-Computer Interfaces in Neurorecovery and Neurorehabilitation.

Michael J Young, David J Lin, Leigh R Hochberg

Open access · greenAbstract read
In one paragraph

Article in Seminars in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 66 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. The Next Frontiers in Preventive and Personalized Healthcare: Artificial Intelligent-powered Solutions.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2025
    Review
  11. Repair mechanisms of the central nervous system: From axon sprouting to remyelination.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  12. Opportunities and Challenges of Brain-on-a-Chip Interfaces.Cyborg and bionic systems (Washington, D.C.) · 2025
    Review
  13. Article
  14. Review
  15. EEG-based sensorimotor neurofeedback for motor neurorehabilitation in children and adults: A scoping review.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024
    Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Michael J YoungDepartment of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
David J LinDepartment of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Leigh R HochbergDepartment of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Allen Institute for Brain Science · USHarvard University · US

Funding

Intuitive, complete neural control of tablet computers for communicationU01DC017844 · NIDCD · BROWN UNIVERSITY · PI HOCHBERG, LEIGH R · 2019 to 2025
$4.3M
High-Bandwidth Wireless Interfaces for Continuous Human Intracortical RecordingUH2NS095548 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI HOCHBERG, LEIGH R, NURMIKKO, ARTO · 2015 to 2019
$3.7M
A Connectome-Based Clinical Trial Platform to Promote Early Recovery of Consciousness after Traumatic ComaDP2HD101400 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI EDLOW, BRIAN L. · 2019 to 2019
$2.5M
Brainstem Network Determinants of Recovery from Traumatic ComaK23NS094538 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI EDLOW, BRIAN L. · 2015 to 2019
$994k
Refining an Advance Care Planning Group Visit intervention – a novel intervention to engage older adults in advance care planningK76AG054782 · NIA · UNIVERSITY OF COLORADO DENVER · PI LUM, HILLARY · 2016 to 2019
$864k
Brainstem Connectome Mapping to Guide Targeted Stimulant Therapy in Patients with Traumatic ComaR21NS109627 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI EDLOW, BRIAN L. · 2019 to 2020
$480k
An Ethical Approach to Detecting Covert ConsciousnessF32MH123001 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI YOUNG, MICHAEL J · 2020 to 2022
$159k
NIDCD NIH HHS U01 DC017844NIMH NIH HHS F32 MH123001NINDS NIH HHS UH2 NS095548RRD VA I01 RX002295RRD VA I50 RX002864RRD VA IK1 RX003563
6 · The paper itself

Abstract

Recent advances in brain-computer interface technology to restore and rehabilitate neurologic function aim to enable persons with disabling neurologic conditions to communicate, interact with the environment, and achieve other key activities of daily living and personal goals. Here we evaluate the principles, benefits, challenges, and future directions of brain-computer interfaces in the context of neurorehabilitation. We then explore the clinical translation of these technologies and propose an approach to facilitate implementation of brain-computer interfaces for persons with neurologic disease.

Indexed as

Brain-Computer InterfacesNeurological RehabilitationActivities of Daily LivingBrainHumans

Identifiers

PMID33742433
PMCPMC8768507
OpenAlexW3138947062

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.