ArticleEuropean journal of dentistry2021
Current Concepts on the Pathogenesis of Peri-implantitis: A Narrative Review.
Article in European journal of dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Under pressure: Unraveling the impact of occlusal overload on peri-implant health-A systematic review.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2025Pooled it
- Impact of rose bengal-mediated antimicrobial photodynamic therapy adjunctive to mechanical debridement on clinical, microbiological, and immunological parameters in peri-implantitis: a parallel, single-blinded, randomized controlled trial.Lasers in medical science · 2025Trial
- Review
- CD38⁺ endothelial remodeling marks spatially patterned vasculopathy in rapidly advancing periodontitis and peri-implantitis.Nature communications · 2026Article
- Enhancing dental implant outcomes in type 2 diabetes: Addressing inflammation and risk factors.World journal of diabetes · 2026Article
- Next-Generation S3-Level Clinical Practice Guidelines in Periodontology: Methodology, Current Evidence, and Future Directions.Dentistry journal · 2026Review
- The impact of DNA extraction methods on species quantification and apparent community composition of in vitro oral biofilms.FEMS microbiology letters · 2026Article
- Inflammatory Mediators in Peri-Implantitis: From Pathophysiology to Therapeutic Targets.Advances in experimental medicine and biology · 2026Review
- Antimicrobial and Antiviral Activities, and Biocompatibility of Titanium Coated with Electron Beam-Irradiated α‑Silver Tungstate Microcrystals.ACS omega · 2025Article
- Evaluation of surface roughness of titanium disks subjected to simulated oral conditions.BMC oral health · 2025Article
- In Vitro Assessment of a Novel Piranha-Passivated Dental Implant Surface Against Oral Biofilm Formation.Clinical oral implants research · 2025Article
- Molecular docking and dynamics simulation of antimicrobial peptides against adhesion proteins of peri-implant pathogens.Scientific reports · 2025Article
- Evaluating the Clinical Efficacy of Membrane-Assisted Regenerative Therapy in Peri-Implantitis Management: A Comprehensive Review Incorporating Systematic Review Evidence.Materials (Basel, Switzerland) · 2025Review
- Numerical Analysis of Laser Thermal Ablation for Gingival and Peri-Implant Inflammation Using Various Laser Irradiation Angles.International journal for numerical methods in biomedical engineering · 2025Article
- CD38bioRxiv : the preprint server for biology · 2025Article
- Association of MMP-8 rs11225395 Polymorphism with the Susceptibility of Peri-Implantitis.Oral health & preventive dentistry · 2025Article
- Article
- The association of gene polymorphisms with peri-implant mucositis and peri-implantitis: A systematic review and meta-analysis.Journal of advanced periodontology & implant dentistry · 2025Article
- Hypoxia-Preconditioned Human Umbilical Cord Mesenchymal Stem Cells Transplantation Ameliorates Inflammation and Bone Regeneration in Peri-Implantitis Rat Model.European journal of dentistry · 2025Article
- Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As implant treatment has been integrated in contemporary dental practice, complications with the forms of peri-implant mucositis and peri-implantitis have also increased in prevalence. Peri-implantitis is the more severe biological complication and is defined as an inflammatory disease affecting peri-implant tissues resulting in bone and eventually implant loss. In addition, the treatment of peri-implantitis has currently become a substantial global economic burden. In the current study, a search was conducted in several electronic databases using specific keywords relevant to the article's main topic. An increasing number of scientific reports have investigated the etiopathology of peri-implant diseases, focusing mainly on peri-implantitis. Microbial biofilm consists an important etiological factor of peri-implant pathology analogous to periodontal diseases. Although several data confirm that peri-implant infections are dominated by gram-negative bacteria, similar to periodontal infections, there is evidence that some cases may harbor a distinct microbiota, including opportunistic microorganisms and/or uncultivable species. Additionally, data support that several parameters, such as genetic predisposition of individual patients, occlusal overload, and local factors such as titanium particles and excess cement, may be implicated in peri-implantitis pathogenesis. Simultaneously, the release of titanium metal particles and their biological consequences or the presence of excess cement in the adjacent peri-implant tissues have also been suggested as factors that contribute to peri-implant pathology. A specific line of research also indicates the role of foreign body response to implant installation. This narrative review aims to discuss the current concepts of etiopathogenetic factors implicated in peri-implantitis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.