Trial reportArchives of orthopaedic and trauma surgery2022
Quadriceps and hamstring tendon autografts in ACL reconstruction yield comparably good results in a prospective, randomized controlled trial.
Trial report in Archives of orthopaedic and trauma surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Quadriceps, hamstring and patella tendon autografts for primary anterior cruciate ligament reconstruction demonstrate similar clinical outcomes, including graft failure, joint laxity and complications: A systematic review with meta-analysis of randomised controlled trials.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Pooled it
- Quadriceps tendon autograft diameters are routinely above 8 mm, and preoperative size estimation before anterior cruciate ligament reconstruction may not be necessary for this graft type: A systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Pooled it
- How statistically fragile are randomized controlled trials comparing quadriceps tendon autografts with hamstring or bone-patellar tendon-bone autografts in anterior cruciate ligament reconstruction?Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Pooled it
- Are Comparable Short-term Outcomes Between Hamstring and Quadriceps Tendon Autografts for ACL Reconstruction Statistically Robust? A Reverse Continuous Fragility Index Analysis of Randomized Controlled Trials.Orthopaedic journal of sports medicine · 2026Review
- Clinical outcomes of quadriceps, hamstring, and bone-patellar tendon-bone autografts for ACL reconstruction: a meta-analysis of randomized controlled trials.Knee surgery & related research · 2026Review
- Sport-Specific Considerations in ACL Reconstruction: Diagnostic Evaluation and Graft Selection.Diagnostics (Basel, Switzerland) · 2026Review
- Age-related differences in MRI signal intensity of the quadriceps and patellar tendons: Implications for ACL graft selection.Journal of experimental orthopaedics · 2026Article
- Hamstring autografts favour knee extension strength recovery while quadriceps autografts optimise flexion strength recovery: A systematic review of randomised controlled trials.Journal of experimental orthopaedics · 2026Review
- Quadriceps tendon-bone vs all soft-tissue autografts for primary anterior cruciate ligament reconstruction: a systematic review and meta-analysis of 7,748 patients.EFORT open reviews · 2025Article
- Quadriceps Tendon Graft Leads to Stronger Flexion and Weaker Extension of the Knee Than Hamstring Graft Post-ACLR: Systematic Review and Meta-Analysis.Indian journal of orthopaedics · 2025Review
- Patients Who Underwent Anterior Cruciate Ligament Reconstruction With an All Soft-Tissue Quadriceps Tendon Graft Had a Greater Return-to-Play Rate Than Patients Who Received a Quadriceps Tendon Bone Graft.Arthroscopy, sports medicine, and rehabilitation · 2025Review
- Global Variations in Surgical Techniques for Primary Anterior Cruciate Ligament Reconstruction at Minimum 2-Year Follow-up: A Systematic Review of Randomized Clinical Trials.Orthopaedic journal of sports medicine · 2025Article
- Innovative Rehabilitation of an Anterior Cruciate Ligament Tear in a Football Player: Muscle Chain Approach-A Case Study.Journal of clinical medicine · 2025Article
- Graft Selection in Anterior Cruciate Ligament Reconstruction: A Comprehensive Review of Current Trends.Medicina (Kaunas, Lithuania) · 2024Review
- Effect of Quadriceps Tendon Autograft Preparation and Fixation on Graft Laxity During Suspensory Anterior Cruciate Ligament Reconstruction: A Biomechanical Analysis.Orthopaedic journal of sports medicine · 2024Article
- Review
- Return to Work After Anterior Cruciate Ligament Reconstruction: A Systematic Review.Orthopaedic journal of sports medicine · 2024Review
- Current trends in graft choice for primary anterior cruciate ligament reconstruction - part II: In-vivo kinematics, patient reported outcomes, re-rupture rates, strength recovery, return to sports and complications.Journal of experimental orthopaedics · 2023Article
- Tibial tunnel enlargement is affected by the tunnel diameter-screw ratio in tibial hybrid fixation for hamstring ACL reconstruction.Archives of orthopaedic and trauma surgery · 2023Article
- Femoral condyle configuration and its impact on anterior cruciate ligament reconstruction.Technology and health care : official journal of the European Society for Engineering and Medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionComparable data of functional outcomes of anterior cruciate ligament reconstruction using either hamstring- or quadriceps tendon grafts is controversial. This prospective, randomized controlled trial aims to provide data comparing both grafts regarding the functional outcome. MATERIALS AND
methodsA two centre trial involving symptomatic patients 18 years of age or older with an anterior cruciate ligament tear was conducted. We randomly assigned 27 patients to quadruple hamstring tendon reconstruction and 24 to quadriceps tendon reconstruction. The patients were evaluated preoperatively, at 3, 6, 12 and 24 months post-surgery. The primary outcome parameter was the side-to-side knee laxity measured with an arthrometer. Secondary outcomes included results in the International Knee Documentation Committee (IKDC) and Lysholm Scores and isokinetic testing of strength in knee extension and flexion.
resultsForty-four patients (86%) completed the 2-year follow-up. There was significantly improved knee stability at all time intervals with no difference between the two study groups. The manual side-to-side displacement improved by 4.7 ± 3.0 mm in patients with hamstring tendon reconstruction and 5.5 ± 2.9 mm in patients with quadriceps tendon reconstruction. In addition, muscle strength and outcome scores (IKDC and Lysholm Score) did not show any differences between the hamstring tendon group and the quadriceps tendon group. Patients in the hamstring tendon group returned to their pre-injury activity level after 95.2 ± 45.5 days while patients in the quadriceps tendon group needed 82.1 ± 45.6 days.
conclusionQuadriceps and hamstring tendon autografts yield comparably good results in primary anterior cruciate ligament reconstruction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.