ArticleCommunications biology2021
Quantitative investigation reveals distinct phases in Drosophila sleep.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Recognition of distinct sleep states in Drosophila uncovers previously obscured homeostatic and circadian control of sleep.Current biology : CB · 2026Article
- Current Evidence for Sleep States inCurrent sleep medicine reports · 2026Review
- Sleep regulation inFrontiers in neuroscience · 2026Review
- Recognition of distinct sleep states inbioRxiv : the preprint server for biology · 2025Article
- Article
- Stem cell-specific ecdysone signaling regulates the development of dorsal fan-shaped body neurons and sleep homeostasis.Current biology : CB · 2024Article
- Article
- Adipose Tissue Exosome circ_sxc Mediates the Modulatory of Adiposomes on Brain Aging by Inhibiting Brain dme-miR-87-3p.Molecular neurobiology · 2024Article
- Article
- Stem cell-specific ecdysone signaling regulates the development and function of abioRxiv : the preprint server for biology · 2023Article
- Balancing Prediction and Surprise: A Role for Active Sleep at the Dawn of Consciousness?Frontiers in systems neuroscience · 2021Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The fruit fly, Drosophila melanogaster, has been used as a model organism for the molecular and genetic dissection of sleeping behaviors. However, most previous studies were based on qualitative or semi-quantitative characterizations. Here we quantified sleep in flies. We set up an assay to continuously track the activity of flies using infrared camera, which monitored the movement of tens of flies simultaneously with high spatial and temporal resolution. We obtained accurate statistics regarding the rest and sleep patterns of single flies. Analysis of our data has revealed a general pattern of rest and sleep: the rest statistics obeyed a power law distribution and the sleep statistics obeyed an exponential distribution. Thus, a resting fly would start to move again with a probability that decreased with the time it has rested, whereas a sleeping fly would wake up with a probability independent of how long it had slept. Resting transits to sleeping at time scales of minutes. Our method allows quantitative investigations of resting and sleeping behaviors and our results provide insights for mechanisms of falling into and waking up from sleep.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.