ArticleScientific reports2021
An exploratory investigation on spatiotemporal parameters, margins of stability, and their interaction in bilateral vestibulopathy.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Pooled it
- Instrumented Walkway Gait Analysis Predicts Fallers in Neurological Disorders: Identifying Digital Biomarkers for Balance Monitoring.Sensors (Basel, Switzerland) · 2026Article
- A modeling approach to understanding poor stability in people with vestibular hypofunction.Journal of biomechanics · 2026Article
- Assessment of dynamic stability and identification of key tasks, inertial sensors, and parameters in patients with bilateral and unilateral vestibulopathy: investigation in a semi-standardized environment.Journal of neuroengineering and rehabilitation · 2026Article
- Probing gait adaptations: The impact of aging on dynamic stability and reflex control mechanisms under varied weight-bearing conditions.European journal of applied physiology · 2025Article
- Inertial data of daily living tasks in bilateral and unilateral vestibulopathy patients and controls.Scientific data · 2025Article
- The effects of weight-bearing manipulations on gait and its underlying neural control mechanisms in toe walking children.Frontiers in human neuroscience · 2025Article
- Gait impairments in patients with bilateral vestibulopathy and chronic unilateral vestibulopathy.Frontiers in neurology · 2025Article
- Optimizing noisy galvanic vestibular stimulation (nGVS) for postural control: methodological considerations when individualizing the signal for people with bilateral vestibulopathy.Frontiers in neurology · 2025Article
- Clinical and instrument-based assessment of balance, gait, and motor functions in pediatric cerebral palsy: A systematic review.Wearable technologies · 2025Review
- Assessment of dynamic stability and identification of key tasks and parameters in patients with unilateral and bilateral vestibulopathy: a laboratory-based study.Frontiers in neuroscience · 2025Article
- Protocol for assessing functional impairments in patients with unilateral and bilateral vestibulopathy: a novel approach to evaluate the impact of vestibular loss in daily life setting.Frontiers in neurology · 2025Article
- Full-body kinematics and head stabilisation strategies during walking in patients with chronic unilateral and bilateral vestibulopathy.Scientific reports · 2024Article
- Article
- The impact of vestibular function on cognitive-motor interference: a case-control study on dual-tasking in persons with bilateral vestibulopathy and normal hearing.Scientific reports · 2023Article
- Bilateral vestibulopathy: a clinical update and proposed diagnostic algorithm.Frontiers in neurology · 2023Review
- Vibrations on mastoid process alter the gait characteristics during walking on different inclines.PeerJ · 2023Article
- Stabilization demands of walking modulate the vestibular contributions to gait.Scientific reports · 2021Article
- Paving the Way Toward Distinguishing Fallers From Non-fallers in Bilateral Vestibulopathy: A Wide Pilot Observation.Frontiers in neurology · 2021Article
- Decoding the bilateral vestibulopathy spectrum: etiology-based phenotypes, clinical profiles and pathways to implant candidacy.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Integration of accurate vestibular, visual, and proprioceptive information is crucial in managing the centre of mass in relation to the base of support during gait. Therefore, bilateral loss of peripheral vestibular function can be highly debilitating when performing activities of daily life. To further investigate the influence of an impaired peripheral vestibular system on gait stability, spatiotemporal parameters, step-to-step variability, and mechanical stability parameters were examined in 20 patients with bilateral vestibulopathy and 20 matched healthy controls during preferred overground walking. Additionally, using a partial least squares analysis the relationship between spatiotemporal parameters of gait and the margins of stability was explored in both groups. Patients with bilateral vestibulopathy showed an increased cadence compared to healthy controls (121 ± 9 vs 115 ± 8 steps/min; p = 0.02; d = 0.77). In addition, although not significant (p = 0.07), a moderate effect size (d = 0.60) was found for step width variability (Coefficient of Variation (%); Bilateral vestibulopathy: 19 ± 11%; Healthy controls: 13 ± 5%). Results of the partial least squares analysis suggest that patients with peripheral vestibular failure implement a different balance control strategy. Instead of altering the step parameters, as is the case in healthy controls, they use the single and double support phases to control the state of the centre of mass to improve the mechanical stability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.