ArticleScientific reports2021
In depth characterisation of the biomolecular coronas of polymer coated inorganic nanoparticles with differential centrifugal sedimentation.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Review
- Terminal sialic acids in the nanoparticle corona modulate cellular uptake.Communications chemistry · 2025Article
- Surface Functionalization of Nanoparticles for Enhanced Electrostatic Adsorption of Biomolecules.Molecules (Basel, Switzerland) · 2025Review
- Multiple Exposures of Plasma to Nanoparticles: A Novel Tool to Personalize Biomolecular Coronas and Fractionate Fluids.Analytical chemistry · 2025Article
- Gold Nanoparticle Adsorption and Uptake are Directed by Particle Capping Agent.Small science · 2025Article
- Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Current and Near-Future Technologies to Quantify Nanoparticle Therapeutic Loading Efficiency and Surface Coating Efficiency with Targeted Moieties.Bioengineering (Basel, Switzerland) · 2025Review
- Protein Corona of Nanoparticles: Isolation and Analysis.Chem & bio engineering · 2024Review
- A Nanoplasmonic Assay for Point-of-Care Detection of Mannose-Binding Lectin in Human Serum.ACS applied materials & interfaces · 2024Article
- Stealth and Biocompatible Gold Nanoparticles through Surface Coating with a Zwitterionic Derivative of Glutathione.Langmuir : the ACS journal of surfaces and colloids · 2024Article
- AdvancingACS bio & med chem Au · 2024Review
- Protocols for isolation and characterization of nanoparticle biomolecular corona complexes.Frontiers in toxicology · 2024Article
- The Why and How of Ultrasmall Nanoparticles.Accounts of chemical research · 2023Article
- Article
- Performance of nanoparticles for biomedical applications: TheBiophysics reviews · 2022Review
- Spiky Gold Nanoparticles for the Photothermal Eradication of Colon Cancer Cells.Nanomaterials (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advances in nanofabrication methods have enabled the tailoring of new strategies towards the controlled production of nanoparticles with attractive applications in healthcare. In many cases, their characterisation remains a big challenge, particularly for small-sized functional nanoparticles of 5 nm diameter or smaller, where current particle sizing techniques struggle to provide the required sensitivity and accuracy. There is a clear need for the development of new reliable characterisation approaches for the physico-chemical characterisation of nanoparticles with significant accuracy, particularly for the analysis of the particles in the presence of complex biological fluids. Herein, we show that the Differential Centrifugal Sedimentation can be utilised as a high-precision tool for the reliable characterisation of functional nanoparticles of different materials. We report a method to correlate the sedimentation shift with the polymer and biomolecule adsorption on the nanoparticle surface, validating the developed core-shell model. We also highlight its limit when measuring nanoparticles of smaller size and the need to use several complementary methods when characterising nanoparticle corona complexes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.