ArticleNPJ primary care respiratory medicine2021
Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population.
Article in NPJ primary care respiratory medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 24 citations in OpenAlex.
- Persistent use of broad-spectrum antibiotics for suspected community acquired urinary tract infections in children in Italian primary care settings.Italian journal of pediatrics · 2026Article
- RSV Detection and Antibiotic Prescribing Decisions for Pediatric Respiratory Tract Infections.JAMA network open · 2026Article
- Social media insights on the introduction of RSV immunoprophylaxis in Italy.Human vaccines & immunotherapeutics · 2025Article
- Exploring different modelling approaches to forecast the community acute respiratory infections burden in children: an Italian epidemiological time series study.BMC public health · 2025Article
- Antibiotic Use in Korean Children Diagnosed With Acute Bronchiolitis: Analysis of the National Health Insurance Reimbursement Data.Journal of Korean medical science · 2024Article
- Bronchiolitis guidelines: what about the Italian situation in a primary care setting?Italian journal of pediatrics · 2023Review
- Different Pediatric Acute Care Settings Influence Bronchiolitis Management: A 10-Year Retrospective Study.Life (Basel, Switzerland) · 2023Article
- UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants.Italian journal of pediatrics · 2023Review
- Prophylaxis protects infants with congenital heart disease from severe forms of RSV infection: an Italian observational retrospective study : Palivizumab prophylaxis in children with congenital heart disease.Italian journal of pediatrics · 2023Observational
- Assessing the burden of bronchiolitis and lower respiratory tract infections in children ≤24 months of age in Italy, 2012-2019.Frontiers in pediatrics · 2023Article
- Antibiotic Prescribing Patterns in Paediatric Primary Care in Italy: Findings from 2012-2018.Antibiotics (Basel, Switzerland) · 2021Article
- COVID-19 Lesson for Respiratory Syncytial Virus (RSV): Hygiene Works.Children (Basel, Switzerland) · 2021Review
- Impact of Guidelines Publication on Acute Bronchiolitis Management: 10-Year Experience from a Tertiary Care Center in Italy.Microorganisms · 2021Article
- A Procalcitonin and C-Reactive Protein-Guided Clinical Pathway for Reducing Antibiotic Use in Children Hospitalized with Bronchiolitis.Children (Basel, Switzerland) · 2021Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Italy, two clinical practice guidelines for the diagnosis and treatment of bronchiolitis were published in October 2014 and December 2015. We evaluated prescriptions for bronchiolitis in children aged 0-24 months before (December 2012-December 2014), in between (December 2014-December 2015) and after (December 2015-December 2018) the guidelines publications. Data were retrieved from the Pedianet database; the measured outcomes were prescriptions rates of antibiotics, corticosteroids, β2-agonists, and other respiratory drugs. In 1011 out of 1581 episodes, patients received at least one treatment, with a total of 2003 prescriptions. The rate of treated bronchiolitis decreased from 66% to 57% (p < 0.001) after the publication of the second guideline; the highest reduction was in younger patients (from 57% to 44%, p = 0.013). Overall antibiotic prescriptions rate did not change, with 31.6% of the patients still receiving them. Our results confirm unnecessary non-evidence-based treatments in the primary care setting, with few changes after the guidelines publications.
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