ArticleNature communications2021
Robust nucleation control via crisscross polymerization of highly coordinated DNA slats.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Programming Dimensional Transitions in DNA Brick Crystals via Interfacial Connectivity.Angewandte Chemie (International ed. in English) · 2026Article
- Hierarchical Assembly of Multilayer Core-Shell DNA Origami Crystals.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- A computational framework for designing micron-scale crisscross DNA megastructures.Nature communications · 2026Article
- Acoustically seeded fabrication of a DNA tesseract into a conductive wire.Nucleic acids research · 2025Article
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- Diamond-lattice photonic crystals assembled from DNA origami.Science (New York, N.Y.) · 2024Article
- Construction of Reconfigurable and Polymorphic DNA Origami Assemblies with Coiled-Coil Patches and Patterns.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Enzyme-Free Exponential Amplification via Growth and Scission of Crisscross Ribbons from Single-Stranded DNA Components.Journal of the American Chemical Society · 2024Article
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- Article
- Recent Advances in DNA Origami-Engineered Nanomaterials and Applications.Chemical reviews · 2023Review
- Multi-micron crisscross structures grown from DNA-origami slats.Nature nanotechnology · 2023Article
- Advancing the Utility of DNA Origami Technique through Enhanced Stability of DNA-Origami-Based Assemblies.Bioconjugate chemistry · 2023Review
- Assembly of Two-Dimensional DNA Arrays Could Influence the Formation of Their Component Tiles.Chembiochem : a European journal of chemical biology · 2022Article
- DNA Nanotechnology-Enabled Fabrication of Metal Nanomorphology.Research (Washington, D.C.) · 2022Review
- Feedback regulation of crystal growth by buffering monomer concentration.Nature communications · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural biomolecular assemblies such as actin filaments or microtubules can exhibit all-or-nothing polymerization in a kinetically controlled fashion. The kinetic barrier to spontaneous nucleation arises in part from positive cooperativity deriving from joint-neighbor capture, where stable capture of incoming monomers requires straddling multiple subunits on a filament end. For programmable DNA self-assembly, it is likewise desirable to suppress spontaneous nucleation to enable powerful capabilities such as all-or-nothing assembly of nanostructures larger than a single DNA origami, ultrasensitive detection, and more robust algorithmic assembly. However, existing DNA assemblies use monomers with low coordination numbers that present an effective kinetic barrier only for slow, near-reversible growth conditions. Here we introduce crisscross polymerization of elongated slat monomers that engage beyond nearest neighbors which sustains the kinetic barrier under conditions that promote fast, irreversible growth. By implementing crisscross slats as single-stranded DNA, we attain strictly seed-initiated nucleation of crisscross ribbons with distinct widths and twists.
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