Evidence map›Paper›PMID 33741723›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Small Extracellular Vesicles Control Dendritic Spine Development through Regulation of HDAC2 Signaling.

Longbo Zhang, Tiffany V Lin, Qianying Yuan, Remy Sadoul, TuKiet T Lam, Angélique Bordey

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Longbo ZhangDepartments of Neurosurgery and Cellular and Molecular Physiology.
Tiffany V LinDepartments of Neurosurgery and Cellular and Molecular Physiology.
Qianying YuanDepartment of Pharmacology, Yale University School of Medicine.
Remy SadoulInstitut de Biologie Structurale, Université Grenoble Alpes, CEA, Centre National de la Recherche Scientifique, Grenoble 38000, France.
TuKiet T LamDepartment of Molecular Biophysics and Biochemistry and W.M. Keck Biotechnology Resource Laboratory, Yale University School of Medicine, New Haven, Connecticut 06520-8082.ORCID 0000-0002-4850-3462
Angélique BordeyDepartments of Neurosurgery and Cellular and Molecular Physiology angelique.bordey@yale.edu.ORCID 0000-0003-3496-3385
Cellular Research (United States) · USCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRW. M. Keck Foundation · USYale University · US

Funding

TSC-mTOR on neuron developmentR01NS086329 · NINDS · YALE UNIVERSITY · PI BORDEY, ANGELIQUE · 2013 to 2017
$1.8M
Nano-UPLC LTQ-Orbitrap Velos MS System for Yale University Keck LaboratoryS10RR031795 · NCRR · YALE UNIVERSITY · PI GULCICEK, EROL E · 2011 to 2011
$600k
NCRR NIH HHS S10 RR031795NINDS NIH HHS R01 NS086329
6 · The paper itself

Abstract

The release of small extracellular vesicles (sEVs) has recently been reported, but knowledge of their function in neuron development remains limited. Using LC-MS/MS, we found that sEVs released from developing cortical neurons

Indexed as

AnimalsCytoplasmDendritic SpinesExosomesExtracellular SpaceFemaleGene Expression Regulation, DevelopmentalHistone Deacetylase 2MaleMicePrimary Cell CultureProteomicsSignal TransductionSynapsesHdac2 protein, mouseHistone Deacetylase 2cortexdevelopmentexosomeHDACspinesynapse

Identifiers

PMID33741723
PMCPMC8084316
OpenAlexW3139133559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.