ArticleCancer discovery2021
Open access · greenAbstract read
In one paragraph
Article in Cancer discovery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 85 citations in OpenAlex.
- Supratentorial ependymoma: a comprehensive review of molecular classification, management strategies, and clinical outcomes (Part II of pediatric ependymomas across compartments).Journal of neuro-oncology · 2026Review
- A brief history of ependymoma.Neuro-oncology · 2026Review
- Article
- Article
- A systems approach identifies MERTK as a therapeutic vulnerability in ZFTA-RELA-driven ependymomas.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Synthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis.Nature cell biology · 2025Article
- Advances in molecular prognostication and treatments in ependymoma.Journal of neuro-oncology · 2025Review
- Targeting EPHB2/ABL1 restores antitumor immunity in preclinical models of ependymoma.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling.Acta neuropathologica communications · 2025Article
- Epigenetic modifications and their roles in pediatric brain tumor formation: emerging insights from chromatin dysregulation.Frontiers in oncology · 2025Review
- Optimizing outcomes in intracranial ependymoma: a contemporary review.Frontiers in oncology · 2025Review
- Article
- YAP, TAZ, and Hippo-Dysregulating Fusion Proteins in Cancer.Annual review of cancer biology · 2024Article
- Glioma.Nature reviews. Disease primers · 2024Review
- Review
- Ependymoma from Benign to Highly Aggressive Diseases: A Review.Advances and technical standards in neurosurgery · 2024Review
- The Intersection of Epigenetic Alterations and Developmental State in Pediatric Ependymomas.Developmental neuroscience · 2024Review
- New Insights into YAP/TAZ-TEAD-Mediated Gene Regulation and Biological Processes in Cancer.Cancers · 2023Review
- Optimizing biomarkers for accurate ependymoma diagnosis, prognostication, and stratification within International Clinical Trials: A BIOMECA study.Neuro-oncology · 2023Article
- Epigenetic Regulation in Primary CNS Tumors: An Opportunity to Bridge Old and New WHO Classifications.Cancers · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 7 institutions in 5 countries.
Robert KuppCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.
Lisa RuffCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.
Sabrina TerranovaCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.
Erica NathanCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.
Stephane BallereauCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.ORCID 0000-0002-8479-3110
Rory StarkCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.ORCID 0000-0002-1790-5469
Chandra Sekhar Reddy ChilamakuriCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.
Nadin HoffmannCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.
Katherine Wickham-RahrmannCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.
Marcus WiddessCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.
Amir ArabzadeDepartment of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas.
Yanhua ZhaoDepartment of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas.
Srinidhi VaradharajanDepartment of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-2033-0758
Tuyu ZhengDivision of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0003-3385-7353
Mohankumar MurugesanCentre for Stem Cell Research, Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu, India.
Stefan M PfisterDivision of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0002-5447-5322
Daisuke KawauchiDepartment of Biochemistry and Cellular Biology, National Center of Neurology and Psychiatry (NCNP), Tokyo, Japan.ORCID 0000-0002-1254-9725
Kristian W PajtlerDivision of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Benjamin DeneenCancer and Cell Biology Program, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas.
Stephen C MackDepartment of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas.ORCID 0000-0001-9620-4742
Katherine E MasihGenetics Branch, Center for Cancer Research, NCI, Bethesda, Maryland.ORCID 0000-0002-0809-668X
Berkley E GryderGenetics Branch, Center for Cancer Research, NCI, Bethesda, Maryland.ORCID 0000-0003-0130-2302
Javed KhanGenetics Branch, Center for Cancer Research, NCI, Bethesda, Maryland.
Richard J GilbertsonCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England. Richard.Gilbertson@cruk.cam.ac.uk.ORCID 0000-0001-7539-9472
Cancer Research UK Cambridge Center · GBBaylor College of Medicine · USCenter for Cancer Research · USGerman Cancer Research Center · DEChildren's Cancer Center · USChristian Medical College, Vellore · INNational Center of Neurology and Psychiatry · JP
Funding
The DNA Damage Response and Tumorigenesis in the BrainP01CA096832 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI BAKER, SUZANNE J. · 2003 to 2025
$38.0MBIOINFORMATICS: SYSTEMS BIOLOGY OF PEDIATRIC CANCERSZIABC011002 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KHAN, JAVED · 2009 to 2025
$9.3MMechanisms and models of C11or95 and C11or95-RELA fusions (RELAFus )U54CA243125 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HOLLAND, ERIC C. · 2019 to 2022
$6.2MAn Investigation of Radial Glia as the Source of Ependymoma Stem CellsR01CA129541 · NCI · UNIVERSITY OF CAMBRIDGE · PI GILBERTSON, RICHARD · 2007 to 2016
$3.0MCancer Research UK 22492Cancer Research UK 26398Cancer Research UK 28598NCI NIH HHS P01 CA096832NCI NIH HHS R01 CA129541NCI NIH HHS U54 CA243125
Abstract
PubMed holds no abstract for this paper.
Indexed as
Cell Transformation, NeoplasticChromatin Assembly and DisassemblyTranslocation, GeneticAnimalsDNA-Binding ProteinsEpendymomaMiceSupratentorial NeoplasmsTranscription Factors2700081o15rik protein, mouseDNA-Binding ProteinsTranscription Factors
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.