ReviewDiabetes care2021
Resolving the Gestational Diabetes Diagnosis Conundrum: The Need for a Randomized Controlled Trial of Treatment.
Review in Diabetes care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Association of maternal blood metabolomics and gestational diabetes mellitus risk: a systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2025Pooled it
- Investigating the Role of Skin Autofluorescence in Gestational Diabetes Mellitus: A Systematic Review.International journal of molecular sciences · 2025Pooled it
- Association between gestational diabetes mellitus and risk of breast cancer: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Pooled it
- Effect of arsenic on the risk of gestational diabetes mellitus: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Changing diagnostic criteria for gestational diabetes (CDC4G) in Sweden: A stepped wedge cluster randomised trial.PLoS medicine · 2024Trial
- Indicators from training healthcare providers on WHO-recommended best practices in prenatal care in Brazil: A before-and-after study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Reduced fetal MAPSE and TAPSE in gestational diabetes mellitus: a prospective case-control study.Irish journal of medical science · 2026Article
- Association Between a Flat Oral Glucose Tolerance Test Pattern and Small-for-Gestational-Age Infants: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Hypertensive disorders of pregnancy: heterogeneity in risk factors and maternal and neonatal outcomes across subtypes-a 6-year retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Comprehensive Review of Gestational Diabetes: Pathophysiology, Pharmacological Management and the Role of Pharmaceutical Care.Current drug safety · 2026Review
- Diabetes in Pregnant Romanian Patients-Epidemiology and Prevention Strategies Proposal.Journal of clinical medicine · 2025Article
- One-step versus two-step screening for gestational diabetes mellitus in Chinese pregnant women: a large non-randomized trial.Endocrine · 2025Article
- Fetal sex and the development of future type 2 diabetes: a 5-year cohort study.Archives of gynecology and obstetrics · 2025Article
- The TANGO-DM randomized controlled trial study protocol: treatment outcomes for gestational diabetes diagnosed according to WHO 2013 or WHO 1999 thresholds.BMC pregnancy and childbirth · 2025Article
- Evaluation of postpartum dysglycemia by serum glycosylated hemoglobin in patients with gestational diabetes mellitus: a national data analysis.Archives of gynecology and obstetrics · 2024Article
- Utilizing the glucose challenge test during pregnancy as a predictor of future diabetes risk.BMC pregnancy and childbirth · 2024Article
- Time to Move Beyond a Binary Criterion for Gestational Diabetes?Reproductive sciences (Thousand Oaks, Calif.) · 2024Review
- Exploring Structural Uncertainty in Cost-Effectiveness Modeling of Gestational Diabetes Screening: An Application Example from Norway.Medical decision making : an international journal of the Society for Medical Decision Making · 2024Article
- Neonatal outcome following metformin-treated gestational diabetes mellitus: A population-based cohort study.Acta obstetricia et gynecologica Scandinavica · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The diagnosis of and criteria for gestational diabetes mellitus (GDM) continue to divide the scientific and medical community, both between and within countries. Many argue for universal adoption of the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria and feel that further clinical trials are unjustified and even unethical. However, there are concerns about the large increase in number of women who would be diagnosed with GDM using these criteria and the subsequent impact on health care resources and the individual. This Perspective reviews the origins of the IADPSG consensus and points out some of its less well-known limitations, particularly with respect to identifying women at risk for an adverse pregnancy outcome. It also questions the clinical and cost-effectiveness data often cited to support the IADPSG glycemic thresholds. We present the argument that adoption of diagnostic criteria defining GDM should be based on response to treatment at different diagnostic thresholds of maternal glycemia. This will likely require an international multicenter trial of treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.