Evidence map›Paper›PMID 33741660›Full record

ArticleBMJ open2021

Importance of accounting for sibling age when examining the association between family size and early childhood cognition, language and emotional behaviour: a birth cohort study.

Christos Symeonides, Peter J Vuillermin, Emma Sciberras, Elizabeth Senn, Sarah M Thomson, Nicole Wardrop, Vicki Anderson, Angela Pezic, Peter D Sly, Anne-Louise Ponsonby and 1 more

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Family Size Across the Life Course and Cognitive Decline in Older Mexican Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christos SymeonidesMurdoch Children's Research Institute,Royal Children's Hospital, University of Melbourne, Parkville, Victoria, Australia.
Peter J VuillerminMurdoch Children's Research Institute,Royal Children's Hospital, University of Melbourne, Parkville, Victoria, Australia.
Emma SciberrasMurdoch Children's Research Institute,Royal Children's Hospital, University of Melbourne, Parkville, Victoria, Australia.
Elizabeth SennMurdoch Children's Research Institute,Royal Children's Hospital, University of Melbourne, Parkville, Victoria, Australia.
Sarah M ThomsonThe Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia.
Nicole WardropMurdoch Children's Research Institute,Royal Children's Hospital, University of Melbourne, Parkville, Victoria, Australia.
Vicki AndersonMurdoch Children's Research Institute,Royal Children's Hospital, University of Melbourne, Parkville, Victoria, Australia.
Angela PezicMurdoch Children's Research Institute,Royal Children's Hospital, University of Melbourne, Parkville, Victoria, Australia.
Peter D SlyChild Health Research Centre, University of Queensland, South Brisbane, Queensland, Australia.
Anne-Louise PonsonbyMurdoch Children's Research Institute,Royal Children's Hospital, University of Melbourne, Parkville, Victoria, Australia annelouise.ponsonby@florey.edu.au.ORCID http://orcid.org/0000-0002-6581-3657
BIS Investigator Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLarger sibships are associated with poorer cognitive and language outcomes but have different impacts on child emotional development. Previous studies have not taken into account sibling age, nor have impacts across multiple neurodevelopmental domains been considered in the same participant group. This study investigated the influence of family size indicators on early childhood cognitive, language and emotional-behavioural development. The effect of sibling age was considered by evaluating these relationships separately for different sibling age categories.

designProspective birth cohort study.

settingParticipants in the Barwon Infant Study were recruited from two major hospitals in the Barwon region of Victoria, Australia, between 2010 and 2013 (n=1074 children).

participantsThe 755 children with any neurodevelopmental data at age 2-3 years excluding twins and those with an acquired neurodisability. OUTCOME MEASURES: Cognitive and language development was assessed using the Bayley Scales of Infant and Toddler Development, Third Edition, and emotional-behavioural development was measured with the Child Behaviour Checklist for Ages 1½-5.

resultsGreater household size was associated with a reduced cognitive development score (adjusted mean difference (AMD) -0.66 per extra household member; 95% CI -0.96 to -0.37; p<0.001) without age-specific differences. However, poorer expressive language was only observed for exposure to siblings between 2-6 and 6-10 years older. Having siblings 2-6 years older was associated with less internalising behaviour (AMD -2.1 per sibling; 95% CI -3.1 to -1.0; p<0.001). These associations persisted after multiple comparison adjustment.

conclusionsThe influence of siblings on early childhood development varies substantially by sibling age and the neurodevelopmental outcome under study. Although family size alone appears important for cognitive development, age-specific findings emphasise the importance of sibling interaction in early childhood expressive language development and emotional behaviour.

Indexed as

CognitionSiblingsChild DevelopmentChild, PreschoolCohort StudiesFamily CharacteristicsHumansProspective StudiesVictoriaepidemiologypaediatricspublic health

Identifiers

PMID33741660
PMCPMC7986776

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.