Evidence map›Paper›PMID 33740919›Full record

ArticleBMC public health2021

The role of contraception in preventing HIV-positive births: global estimates and projections.

Jennifer Sherwood, Elise Lankiewicz, Beirne Roose-Snyder, Bergen Cooper, Austin Jones, Brian Honermann

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jennifer SherwoodPublic Policy Office, amfAR, Foundation for AIDS Research, 1100 Vermont Avenue NW, Suite 600, District of Columbia, Washington, DC, 20005, USA. Jennifer.sherwood@amfar.org.ORCID 0000-0003-2814-1684
Elise LankiewiczPublic Policy Office, amfAR, Foundation for AIDS Research, 1100 Vermont Avenue NW, Suite 600, District of Columbia, Washington, DC, 20005, USA.
Beirne Roose-SnyderCenter for Health and Gender Equity (CHANGE), Washington DC, USA.
Bergen CooperCenter for Health and Gender Equity (CHANGE), Washington DC, USA.
Austin JonesPublic Policy Office, amfAR, Foundation for AIDS Research, 1100 Vermont Avenue NW, Suite 600, District of Columbia, Washington, DC, 20005, USA.
Brian HonermannPublic Policy Office, amfAR, Foundation for AIDS Research, 1100 Vermont Avenue NW, Suite 600, District of Columbia, Washington, DC, 20005, USA.
American Foundation for AIDS Research · USCenter for Health and Gender Equity · USJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMeeting the contraceptive needs of women living with HIV (WLHIV) has primary health benefits for women, in addition to being a key element to prevent mother-to-child HIV transmission. This analysis will estimate the current number of infant HIV infections prevented by contraception in the era of increased HIV treatment coverage and; 2) model the additional HIV benefits of preventing unintended births to WLHIV.

methodsSecondary data analysis was conducted using publicly available data from the United Nations Programme on HIV/AIDS (UNAIDS) and Population Division, Demographic Health Surveys, and peer-review literature. National data from 70 countries, that had a UNAIDS estimate for the number of WLHIV nationally, were combined into country-level models. Models estimated the current number of infant HIV infections averted by contraception annually and potentially averted if unintended births to WLHIV were prevented. Estimates take into account pregnancy and live birth rates, contraceptive coverage, contraceptive method mix and failure rates, and HIV treatment coverage during pregnancy to prevent mother to child transmission.

resultsContraception use among WLHIV prevents an estimated 43,559 new infant HIV infections annually across 70 countries. Countries with the largest number of infant infections averted by contraception included South Africa (9441), Nigeria (4195), Kenya (3508), Zimbabwe (2586), and India (2145). Preventing unintended births to WLHIV could avert an additional 43,768 new infant infections per year, with the greatest potential gains to be made in South Africa (12,036), Nigeria (2770), Uganda (2552), and the Democratic Republic of the Congo (2324).

conclusionsContraception continues to play an integral role in global HIV prevention efforts in the era of increasing HIV treatment coverage, especially in sub-Saharan Africa. Broad contraceptive availability, increased contraceptive voluntarism and method mix are key components to preventing unintended births and ending new infant HIV infections worldwide.

Indexed as

HIV InfectionsChildContraceptionContraception BehaviorFamily Planning ServicesFemaleHumansIndiaInfectious Disease Transmission, VerticalKenyaNigeriaPregnancySouth AfricaUgandaZimbabweAntenatal HIVContraceptionFamily planningHIVPreventionWomen

Identifiers

PMID33740919
PMCPMC7977320
OpenAlexW3137171127

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.