Evidence map›Paper›PMID 33740447›Full record

ArticleCell2021

Precision medicine in 2030-seven ways to transform healthcare.

Joshua C Denny, Francis S Collins

Abstract read
In one paragraph

Article in Cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 177 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
177citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

177 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
  4. Review
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  8. Article
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  11. Moving from Bench to Bedside: A Social History of Actionability in Biomedicine.medRxiv : the preprint server for health sciences · 2026
    Article
  12. What Is Precision Psychotherapy?The Journal of medicine and philosophy · 2026
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Observational

117 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joshua C DennyAll of Us Research Program, National Institutes of Health, Bethesda, MD, USA. Electronic address: joshua.denny@nih.gov.
Francis S CollinsNational Institutes of Health, Bethesda, MD, USA.

Funding

Genetic analysis of type II diabetes in Finnish populationZIAHG000024 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI ERDOS, MICHAEL · 2009 to 2025
$38.2M
Improving precision health approaches through large-scale EHRs and biobanksZIAHG200417 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI DENNY, JOSHUA · 2022 to 2024
$4.2M
Intramural NIH HHS Z99 OD999999Intramural NIH HHS ZIA HG200417
6 · The paper itself

Abstract

Precision medicine promises improved health by accounting for individual variability in genes, environment, and lifestyle. Precision medicine will continue to transform healthcare in the coming decade as it expands in key areas: huge cohorts, artificial intelligence (AI), routine clinical genomics, phenomics and environment, and returning value across diverse populations.

Indexed as

Delivery of Health CarePrecision MedicineArtificial IntelligenceBig DataBiomedical ResearchCultural DiversityElectronic Health RecordsHumansPhenomics

Identifiers

PMID33740447
PMCPMC9616629

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.