Evidence map›Paper›PMID 33739987›Full record

ArticlePloS one2021

Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study.

Hamid Zaferani Arani, Giti Dehghan Manshadi, Hesam Adin Atashi, Aida Rezaei Nejad, Seyyed Mojtaba Ghorani, Soheila Abolghasemi, Maryam Bahrani, Homayoon Khaledian, Pantea Bozorg Savodji, Mohammad Hoseinian and 2 more

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Obesity as an independent risk factor for COVID-19 severity and mortality.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hamid Zaferani AraniYoung Researchers and Elite Club, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Giti Dehghan ManshadiDepartment of Anesthesiology and Critical Care, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Hesam Adin AtashiYoung Researchers and Elite Club, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.ORCID 0000-0003-3558-204X
Aida Rezaei NejadStem Cell and Regenerative Medicine Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-7737-7824
Seyyed Mojtaba GhoraniYoung Researchers and Elite Club, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.ORCID 0000-0002-1683-1816
Soheila AbolghasemiDepartment of Infectious Diseases, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Maryam BahraniDepartment of Emergency Medicine, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.ORCID 0000-0001-5570-3246
Homayoon KhaledianYoung Researchers and Elite Club, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Pantea Bozorg SavodjiYoung Researchers and Elite Club, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Mohammad HoseinianYoung Researchers and Elite Club, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.ORCID 0000-0001-7752-2681
Atefe Kazemzade BejandiYoung Researchers and Elite Club, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.ORCID 0000-0001-5382-0086
Shahla AbolghasemiTehran Medical Sciences, Islamic Azad University, Tehran, Iran.ORCID 0000-0002-4355-5271

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last months of the coronavirus pandemic, with all those public restrictions and health interventions, the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears now to have been raised in some countries around the world. Iran was one of those first countries facing the second wave of coronavirus, due to the lack of appropriate public restrictions because of economic problems the country is facing. The clinical and demographic characteristics of severe cases and non-severe cases of Coronavirus Disease (COVID-19) in 192 patients in Tehran, Iran, between June 16 and July 11, 2020, were investigated. The patients were divided into severe cases (n = 82) and non-severe cases (n = 110). Demographic and clinical characteristics were compared between the two study clusters. The mean age was 54.6 ± 17.2 years, and the most common presenting symptom was persistent cough (81.8%) and fever (79.7%). The logistic regression model revealed that age, BMI, and affected family members were statistically associated with severity. Patients with complicated conditions of disorders faced more hospitalization days and medical care than the average statistical data. As the coronavirus spike in the case and death reports from June 2020, we observed the rise in the incidence of severe cases, where 42.7% (82/192) of cases have resulted in severe conditions. Our findings also suggested that the effect of IFB (Betamethasone) was more valid than the other alternative drugs such as LPV/r and IVIg.

Indexed as

AdultAgedBetamethasoneBody Mass IndexCoughCOVID-19COVID-19 Drug TreatmentFemaleFeverHumansImmunoglobulins, IntravenousIranLogistic ModelsMaleMiddle AgedPandemicsBetamethasoneImmunoglobulins, Intravenous

Identifiers

PMID33739987
PMCPMC7979149

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.