ArticleJournal of veterinary internal medicine2021
Assessment of bacterial and fungal populations in urine from clinically healthy dogs using next-generation sequencing.
Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Carbapenem-Resistant Organisms in Companion Animals in New York City, 2019-2022.Open forum infectious diseases · 2025Article
- Article
- Evaluation of the vaginal and urinary microbiota of healthy cycling bitches.BMC veterinary research · 2024Article
- Dietary Features Are Associated with Differences in the Urinary Microbiome in Clinically Healthy Adult Dogs.Veterinary sciences · 2024Article
- The Impact of Microorganisms on Canine Semen Quality.Animals : an open access journal from MDPI · 2024Article
- Domestic dogs maintain clinical, nutritional, and hematological health outcomes when fed a commercial plant-based diet for a year.PloS one · 2024Article
- The impact of urine collection method on canine urinary microbiota detection: a cross-sectional study.BMC microbiology · 2023Article
- Review
- Characterization of the urogenital microbiome in Miniature Schnauzers with and without calcium oxalate urolithiasis.Journal of veterinary internal medicine · 2022Article
- The Urinary Resistome of Clinically Healthy Companion Dogs: Potential One Health Implications.Antibiotics (Basel, Switzerland) · 2022Article
- Article
- Assessment of bacterial and fungal populations in urine from clinically healthy dogs using next-generation sequencing.Journal of veterinary internal medicine · 2021Article
- Article
- Longitudinal examination of urine pH, specific gravity, protein, culture, and antimicrobial resistance profiles in healthy dogs.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundUrine from clinically healthy dogs is not sterile. Characterizing microbial diversity and abundance within this population of dogs is important to define normal reference ranges for healthy urine.
objectivesTo establish composition and relative representation of bacterial and fungal microbiomes in urine of clinically healthy dogs. ANIMALS: Fifty clinically healthy dogs.
methodsAnalytic study. Urine sampling via cystocentesis. Comprehensive evaluation of urine including standard urinalysis, culture and sensitivity, next-generation sequencing (NGS), and bioinformatics to define bacterial and fungal microbiome.
resultsCulture did not yield positive results in any samples. Next-generation sequencing of urine established low presence of bacteria, fungi, or both in all samples. Diversity and abundance of bacterial and fungal communities varied between urine samples from different dogs. Struvite crystals were associated with bacterial community structure (P = .07) and there was a positive correlation between struvite crystals and pH. CONCLUSIONS AND CLINICAL IMPORTANCE: The microbiome in urine of clinically healthy dogs has diverse bacterial and fungal species These findings highlight limitations of conventional culture testing and the need for culture-independent molecular diagnostics to detect microorganisms in urine.
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