Evidence map›Paper›PMID 33739448›Full record

ArticleBiometrics2022

Sparse linear discriminant analysis for multiview structured data.

Sandra E Safo, Eun Jeong Min, Lillian Haine

Abstract read
In one paragraph

Article in Biometrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Integrative Analysis of Multimodal Omics Data.Annual review of statistics and its application · 2026
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  11. Molecular Evaluation of the mRNA Expression of theJournal of fungi (Basel, Switzerland) · 2024
    Article
  12. Article
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  15. mvlearnR and Shiny App for multiview learning.Bioinformatics advances · 2024
    Article
  16. Article
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  20. sJIVE: Supervised Joint and Individual Variation Explained.Computational statistics & data analysis · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sandra E SafoDivision of Biostatistics, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0001-9593-4778
Eun Jeong MinDepartment of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Lillian HaineDivision of Biostatistics, University of Minnesota, Minneapolis, Minnesota, USA.

Funding

Institutional Career Development CoreKL2TR002492 · NCATS · UNIVERSITY OF MINNESOTA · PI INGBAR, DAVID H · 2018 to 2022
$6.3M
Training in Biostatistics for Heart, Lung and Blood Disease ResearchT32HL129956 · NHLBI · UNIVERSITY OF MINNESOTA · PI NEATON, JAMES DENNIS · 2016 to 2020
$1.1M
NCATS NIH HHS KL2 TR002492NHLBI NIH HHS T32 HL129956
6 · The paper itself

Abstract

Classification methods that leverage the strengths of data from multiple sources (multiview data) simultaneously have enormous potential to yield more powerful findings than two-step methods: association followed by classification. We propose two methods, sparse integrative discriminant analysis (SIDA), and SIDA with incorporation of network information (SIDANet), for joint association and classification studies. The methods consider the overall association between multiview data, and the separation within each view in choosing discriminant vectors that are associated and optimally separate subjects into different classes. SIDANet is among the first methods to incorporate prior structural information in joint association and classification studies. It uses the normalized Laplacian of a graph to smooth coefficients of predictor variables, thus encouraging selection of predictors that are connected. We demonstrate the effectiveness of our methods on a set of synthetic datasets and explore their use in identifying potential nontraditional risk factors that discriminate healthy patients at low versus high risk for developing atherosclerosis cardiovascular disease in 10 years. Our findings underscore the benefit of joint association and classification methods if the goal is to correlate multiview data and to perform classification.

Indexed as

Discriminant AnalysisHumanscanonical correlation analysisintegrative analysisjoint association and classificationLaplacianmultiple sources of datapathway analysissparsity

Identifiers

PMID33739448
PMCPMC8906173

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.