ArticleMolecular biology and evolution2021
Rubisco Adaptation Is More Limited by Phylogenetic Constraint Than by Catalytic Trade-off.
Article in Molecular biology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Machine learning-assisted directed evolution of plant Rubisco.Science advances · 2026Article
- Rubisco kinetic diversity and effectiveness of CO2-concentrating mechanisms in aquatic photosynthetic organisms.Plant physiology · 2026Review
- A glance at the hidden diversity of Rubisco and CO2-concentrating mechanisms in cyanobacteria.Plant physiology · 2026Article
- Variance in Calvin-Benson cycle intermediate levels between closely related species in the tomato clade.Journal of experimental botany · 2026Article
- Diversity in Rubisco kinetics and CO2-concentrating mechanisms in Cyanobacteria.Plant physiology · 2026Article
- Calculation of specificity constants Γ for RUBISCO of different species from microcalorimetric data.Photosynthesis research · 2025Article
- Rubisco is slow across the tree of life.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Understanding carboxysomes to enhance carbon fixation in crops.Biochemical Society transactions · 2025Review
- Chemoautotrophy in subzero environments and the potential for cold-adapted Rubisco.Applied and environmental microbiology · 2025Article
- A phylogenetic approach to comparative genomics.Nature reviews. Genetics · 2025Review
- Enzymatic and quantitative properties of Rubisco in some conifers and lycopods.Journal of plant research · 2025Article
- Rubisco is evolving for improved catalytic efficiency and COProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Equisetum praealtum and E. hyemale have abundant Rubisco with a high catalytic turnover rate and low COJournal of plant research · 2024Article
- Engineering Rubisco to enhance COSynthetic and systems biotechnology · 2024Review
- Comparative physiology of canopy tree leaves in evergreen and deciduous forests in lowland Thailand.Scientific data · 2023Article
- The Evolutionary Constraints on Angiosperm Chloroplast Adaptation.Genome biology and evolution · 2023Article
- Singular adaptations in the carbon assimilation mechanism of the polyextremophile cyanobacterium Chroococcidiopsis thermalis.Photosynthesis research · 2023Article
- The trajectory in catalytic evolution of Rubisco in Posidonia seagrass species differs from terrestrial plants.Plant physiology · 2023Article
- Predicting plant Rubisco kinetics from RbcL sequence data using machine learning.Journal of experimental botany · 2023Article
- Red Rubiscos and opportunities for engineering green plants.Journal of experimental botany · 2023Review
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10 authors.
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Abstract
Rubisco assimilates CO2 to form the sugars that fuel life on earth. Correlations between rubisco kinetic traits across species have led to the proposition that rubisco adaptation is highly constrained by catalytic trade-offs. However, these analyses did not consider the phylogenetic context of the enzymes that were analyzed. Thus, it is possible that the correlations observed were an artefact of the presence of phylogenetic signal in rubisco kinetics and the phylogenetic relationship between the species that were sampled. Here, we conducted a phylogenetically resolved analysis of rubisco kinetics and show that there is a significant phylogenetic signal in rubisco kinetic traits. We re-evaluated the extent of catalytic trade-offs accounting for this phylogenetic signal and found that all were attenuated. Following phylogenetic correction, the largest catalytic trade-offs were observed between the Michaelis constant for CO2 and carboxylase turnover (∼21-37%), and between the Michaelis constants for CO2 and O2 (∼9-19%), respectively. All other catalytic trade-offs were substantially attenuated such that they were marginal (<9%) or non-significant. This phylogenetically resolved analysis of rubisco kinetic evolution also identified kinetic changes that occur concomitant with the evolution of C4 photosynthesis. Finally, we show that phylogenetic constraints have played a larger role than catalytic trade-offs in limiting the evolution of rubisco kinetics. Thus, although there is strong evidence for some catalytic trade-offs, rubisco adaptation has been more limited by phylogenetic constraint than by the combined action of all catalytic trade-offs.
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