ReviewGenome biology and evolution2021
The Genomic Architecture and Evolutionary Fates of Supergenes.
Review in Genome biology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
62 citing papers in PubMed, 13 citations in OpenAlex.
- Developmental bias of body size and caste by the fire ant social supergene.Proceedings. Biological sciences · 2026Article
- Polygenic and monogenic adaptation drive evolutionary rescue at different magnitudes of environmental change.The Journal of heredity · 2026Article
- Balanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- A T2T Genome of the Lobed-Lip Iguazu Joana (Crenicichla tuca) Reveals Intrachromosomal Rearrangements and Trans-species Polymorphism in Cichlid Fishes.Genome biology and evolution · 2026Article
- Distinct genomic architectures but the same gene underlie the convergent evolution of a plant supergene.Science advances · 2026Article
- Ancient but dynamic: structural expansion, massive gene duplication, and transposable element colonization in a supergene controlling ant social organization.Molecular biology and evolution · 2026Article
- Multiple Origins of a Sex Ratio Supergene in Formica Ants.Molecular biology and evolution · 2026Article
- Genomic architecture and evolution of heterostyly: new insights from Cordia subcordata (Boraginaceae).Molecular biology and evolution · 2026Article
- Article
- Balanced polymorphism in a floral transcription factor underlies an ancient rhythm of daily sex alternation in avocado.bioRxiv : the preprint server for biology · 2025Article
- Genome architecture evolution in an invasive copepod species complex.Nature communications · 2025Article
- Distinct haplotypes and reversed dominance at a single-gene balanced polymorphism controlling heterodichogamy in two genera of wingnuts.Current biology : CB · 2025Article
- A Novel Supergene Controls Queen Size and Colony Social Organization in the Ant Myrmica ruginodis.Molecular biology and evolution · 2025Article
- Functional genetic elements of a butterfly mimicry supergene.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Genomic studies in Linum shed light on the evolution of the distyly supergene and the molecular basis of convergent floral evolution.The New phytologist · 2025Article
- Evolution of petal patterning: blooming floral diversity at the microscale.The New phytologist · 2025Review
- A Balanced Inversion Polymorphism Exhibits a Dominance Reversal at the Gene Expression Level that Depends on Developmental Context.Molecular biology and evolution · 2025Article
- Chromosomal Inversions Mediated by Tandem Insertions of Transposable Elements.Genome biology and evolution · 2025Article
- The Genomic Basis of the Tristylous Floral Polymorphism: Evidence for a Role of Gene Duplications in a Region of Restricted Recombination.Molecular biology and evolution · 2025Article
- Exposing Selection and Genetic Linkage in the Evolutionary Enigmatic Balanced Lethal System inEcology and evolution · 2025Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Supergenes are genomic regions containing sets of tightly linked loci that control multi-trait phenotypic polymorphisms under balancing selection. Recent advances in genomics have uncovered significant variation in both the genomic architecture as well as the mode of origin of supergenes across diverse organismal systems. Although the role of genomic architecture for the origin of supergenes has been much discussed, differences in the genomic architecture also subsequently affect the evolutionary trajectory of supergenes and the rate of degeneration of supergene haplotypes. In this review, we synthesize recent genomic work and historical models of supergene evolution, highlighting how the genomic architecture of supergenes affects their evolutionary fate. We discuss how recent findings on classic supergenes involved in governing ant colony social form, mimicry in butterflies, and heterostyly in flowering plants relate to theoretical expectations. Furthermore, we use forward simulations to demonstrate that differences in genomic architecture affect the degeneration of supergenes. Finally, we discuss implications of the evolution of supergene haplotypes for the long-term fate of balanced polymorphisms governed by supergenes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.