ReviewCardiovascular research2022
Current progress in clinical, molecular, and genetic aspects of adult fibromuscular dysplasia.
Review in Cardiovascular research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Characteristics of Asian patients with Fibromuscular Dysplasia: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Pooled it
- Evolving cerebrovascular pathology in fibromuscular dysplasia leading to aneurysmal subarachnoid hemorrhage.Radiology case reports · 2026Article
- Bilateral internal carotid artery fibromuscular dysplasia identified during acute ischemic stroke evaluation: A case report.Radiology case reports · 2026Article
- Prevalence, Predictors, and Clinical Outcomes of Cervical Arterial Dissection in Patients with Spontaneous Coronary Artery Dissection: A Multicenter Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Role of 99mTc-DTPA Captopril Renal Scintigraphy in the Diagnosis of Renal Fibromuscular Dysplasia: A Case Report.Cureus · 2026Article
- Cerebrovascular fibromuscular dysplasia.Therapeutic advances in neurological disorders · 2026Review
- Article
- Case Report: Endovascular thrombectomy for acute ischemic stroke with bilateral internal carotid artery fibromuscular dysplasia.Frontiers in cardiovascular medicine · 2025Article
- Moyamoya Disease and Carotid Web in a Young Adult With Ischemic Stroke: A Case Report.Clinical case reports · 2024Article
- Identifying a gene-regulatory network that drives fibromuscular dysplasia.Nature cardiovascular research · 2024Article
- Evidence for routine brain-to-pelvis imaging and antiplatelet therapy in patients diagnosed with fibromuscular dysplasia.Journal of clinical hypertension (Greenwich, Conn.) · 2024Review
- Cerebral arteriopathies of childhood and stroke - A focus on systemic arteriopathies and pediatric fibromuscular dysplasia (FMD).Vascular medicine (London, England) · 2024Review
- Vascular Diseases in Women: Do Women Suffer from Them Differently?Journal of clinical medicine · 2024Review
- Next Generation Sequencing and Electromyography Reveal the Involvement of theCurrent issues in molecular biology · 2024Article
- Spontaneous coronary artery dissection and fibromuscular dysplasia: insights into recent developments.Frontiers in cardiovascular medicine · 2024Review
- Fibromuscular Dysplasia: Three Cases to Highlight a Requirement for Surveillance Strategy Optimization.Cureus · 2023Article
- Fibromuscular Dysplasia Presenting as Acute Unilateral Renal Infarction: A Case Report and Review of Two Diseases.Cureus · 2023Article
- Cerebrovascular Fibromuscular Dysplasia - A Practical Review.Vascular health and risk management · 2023Review
- Association of Spontaneous Coronary Artery Dissection With Atrial Arrhythmias.The American journal of cardiology · 2023Observational
- Fibromuscular dysplasia in a middle-aged transgender man: The role of hormones in disease pathogenesis.SAGE open medical case reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 14 institutions in 8 countries.
Funding
Abstract
Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease that may involve medium-sized muscular arteries throughout the body. The majority of FMD patients are women. Although a variety of genetic, mechanical, and hormonal factors play a role in the pathogenesis of FMD, overall, its cause remains poorly understood. It is probable that the pathogenesis of FMD is linked to a combination of genetic and environmental factors. Extensive studies have correlated the arterial lesions of FMD to histopathological findings of arterial fibrosis, cellular hyperplasia, and distortion of the abnormal architecture of the arterial wall. More recently, the vascular phenotype of lesions associated with FMD has been expanded to include arterial aneurysms, dissections, and tortuosity. However, in the absence of a string-of-beads or focal stenosis, these lesions do not suffice to establish the diagnosis. While FMD most commonly involves renal and cerebrovascular arteries, involvement of most arteries throughout the body has been reported. Increasing evidence highlights that FMD is a systemic arterial disease and that subclinical alterations can be found in non-affected arterial segments. Recent significant progress in FMD-related research has led to improve our understanding of the disease's clinical manifestations, natural history, epidemiology, and genetics. Ongoing work continues to focus on FMD genetics and proteomics, physiological effects of FMD on cardiovascular structure and function, and novel imaging modalities and blood-based biomarkers that can be used to identify subclinical FMD. It is also hoped that the next decade will bring the development of multi-centred and potentially international clinical trials to provide comparative effectiveness data to inform the optimal management of patients with FMD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.