ArticleAging2021
Association between cognitive health and masticatory conditions: a descriptive study of the national database of the universal healthcare system in Japan.
Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Association Between Oral Frailty and Cognitive Impairment in Older Adults: A Cross-sectional Study.International dental journal · 2026Article
- Exploring the link between tooth loss, cognitive function, and brain wellness in the context of healthy aging.Journal of periodontal research · 2024Article
- Denture use and a slower rate of cognitive decline among older adults with partial tooth loss in China: A 10-year prospective cohort study.Aging medicine (Milton (N.S.W)) · 2024Article
- Exploring the contribution of Japan's experience in addressing rapid aging in Asia: Focus on dementia care.Global health & medicine · 2024Review
- Unhealthy oral status contributes to the older patients with cognitive frailty: an analysis based on a 5-year database.BMC geriatrics · 2022Article
- Condylar Asymmetry in Children with Unilateral Posterior Crossbite Malocclusion: A Comparative Cross-Sectional Study.Children (Basel, Switzerland) · 2022Article
- Musculoskeletal Deficits and Cognitive Impairment: Epidemiological Evidence and Biological Mechanisms.Current osteoporosis reports · 2022Review
- The Sedentary Lifestyle and Masticatory Dysfunction: Time to Review the Contribution to Age-Associated Cognitive Decline and Astrocyte Morphotypes in the Dentate Gyrus.International journal of molecular sciences · 2022Review
- Cognitive impairment and edentulism among older adults: an observational study using claims data.BMC geriatrics · 2022Observational
- A cross-sectional survey of patient's perception and knowledge of dental implants in Japan.International journal of implant dentistry · 2022Article
- Association between occlusal support, salivary amyloid-β42 levels, and cognitive function in older adults: A cross-sectional pilot study.Journal of Alzheimer's disease reportsArticle
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cognitive health is subject to decline with increasing numbers of lost teeth which impacts mastication. This study is a descriptive data analysis of the association between masticatory and cognitive conditions using a large database. We obtained the dental and medical records from Japan's universal healthcare system (UHCS) from the national database in 2017. The data from 94% of the Japanese population aged 65 and over is included. It is inclusive of diagnostic codes for various types of cognitive impairment, as well as dental treatment records from 2012 to 2017. The cognitive impairment group was compared to those without a diagnosis of cognitive impairment. Crude odds ratio between loss of mastication with natural teeth (exposure) and cognitive impairments (outcome) were compared. Patients who have lost masticatory function are likely to have cognitive impairment with an odds ratio of 1.89 (p<0.0001) for early elderly (aged 65-75) and 1.33 (p<0.0001) for advanced elderly (over 75). Patients who are edentulous and function with complete dentures are likely to have cognitive impairment with an odds ratio of 2.38 (p<0.0001) and 1.38 (p<0.0001), respectively. The data shows a convincing and significant result of an association between cognitive health and oral health, related to masticatory conditions.
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Registered trials
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