ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2021
Validation of home portable monitoring for the diagnosis of sleep-disordered breathing in adolescents and adults with neuromuscular disorders.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Home-testing devices for diagnosing obstructive sleep apnoea hypopnoea syndrome - a systematic review and economic evaluation.Health technology assessment (Winchester, England) · 2026Pooled it
- Nocturnal polygraphy in neuromuscular disorders: is it a useful diagnostic tool?Arquivos de neuro-psiquiatria · 2026Article
- Characteristics of obstructive sleep apnea in children with cerebral palsy: a comparative study with healthy children.European journal of medical research · 2025Article
- Detection of sleep apnea using smartphone-embedded inertial measurement unit.Scientific reports · 2025Article
- Comparing home polysomnography with transcutaneous COJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Detection of sleep apnea using only inertial measurement unit signals from apple watch: a pilot-study with machine learning approach.Sleep & breathing = Schlaf & Atmung · 2025Article
- Piezoelectric rubber sheet sensor: a promising tool for home sleep apnea testing.Sleep & breathing = Schlaf & Atmung · 2024Article
- Quantitative detection of sleep apnea in adults using inertial measurement unit embedded in wristwatch wearable devices.Scientific reports · 2024Article
- Validation of a portable monitor compared with polysomnography for screening of obstructive sleep apnea in polio survivors.Frontiers in neurology · 2023Article
- Home portable monitoring for the diagnosis of sleep-disordered breathing in adolescents and adults with neuromuscular disorders: not yet ready for prime time.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesSleep-disordered breathing (SDB) is common in patients with neuromuscular disorders (NMD), developing before chronic hypercapnia appears. Polysomnography (PSG) is the diagnostic gold standard but is often impractical and poorly accessible for individuals with NMD. We sought to determine the diagnostic accuracy, feasibility, and patient preference of home sleep apnea testing (HSAT) compared with PSG for the detection of SDB in NMD.
methodsParticipants with NMD at risk for SDB aged ≥ 13 years underwent HSAT followed by overnight PSG with concomitant laboratory sleep apnea testing (same device as HSAT). Sensitivity and specificity were calculated for standard apnea-hypopnea index cutoffs for mild (≥ 5 events/h), moderate (≥ 15 events/h), and severe SDB (≥ 30 events/h) and for an oxygen desaturation index ≥ 5 events/h. Receiver operating characteristic curves were built. A questionnaire assessed patient preference.
resultsOf 38 participants, 73% had moderate to severe SDB and 79% had technically acceptable HSAT. For an apnea-hypopnea index ≥ 15 events/h, HSAT sensitivity and specificity were 50% and 88%, respectively. For an oxygen desaturation index ≥ 5 events/h, HSAT sensitivity and specificity were 95% and 78%, respectively. The area under the receiver operating characteristic curve for an apnea-hypopnea index ≥ 15 events/h was 0.88 (95% confidence interval, 0.69-1.00) for HSAT. The HSAT underestimated the apnea-hypopnea index from PSG (bias, -10.7 ± 15.9 events/h). HSAT was preferred to PSG by 61% of participants.
conclusionsHSAT is feasible, preferred by patients, and reliable for detecting SDB in most patients, although it cannot definitively rule out SDB. Therefore, HSAT is a viable diagnostic approach for SDB in NMD when PSG is not feasible, recognizing that it does not accurately distinguish between upper-airway obstruction and hypoventilation. Additional work is needed to further optimize home sleep testing in NMD. CITATION: Westenberg JN, Petrof BJ, Noel F, et al. Validation of home portable monitoring for the diagnosis of sleep-disordered breathing in adolescents and adults with neuromuscular disorders.
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