Evidence map›Paper›PMID 33739156›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2021

Soluble guanylate cyclase stimulation in late gestation does not mitigate asymmetric intrauterine growth restriction or cardiovascular risk induced by placental ischemia in the rat.

Laura E Coats, Bhavisha A Bakrania, Daniel R Bamrick-Fernandez, Allison M Ariatti, Adam Z Rawls, Norma B Ojeda, Barbara T Alexander

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Guidelines for in vivo models of developmental programming of cardiovascular disease risk.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Laura E CoatsDepartment of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi.
Bhavisha A BakraniaDepartment of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi.ORCID 0000-0002-2534-004X
Daniel R Bamrick-FernandezDepartment of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi.
Allison M AriattiDepartment of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi.
Adam Z RawlsDepartment of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi.
Norma B OjedaDepartment of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi.ORCID 0000-0001-6353-2731
Barbara T AlexanderDepartment of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi.
Jackson Memorial Hospital · USThe University of Queensland · AUUniversity of Mississippi Medical Center · US

Funding

STRUCTURAL VASCULAR ADAPTATION OF THE MICROCIRCULATIONP01HL051971 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI HALL, JOHN E · 1993 to 2018
$39.4M
Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Babbette LaMarca, Jane F Reckelhoff · 2017 to 2026
$26.4M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI TAYLOR, ERIN BASSFORD · 2013 to 2022
$23.4M
Hypertension and Cardiorenal Research Training ProgramT32HL105324 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI Joey P. Granger · 2010 to 2026
$7.8M
Hypertension in Adult IUGR Offspring: Beneficial Effects of Perinatal InterventionR01HL143459 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI ALEXANDER, BARBARA T · 2020 to 2022
$1.4M
Hypertension in Adult IUGR Offspring: Beneficial Effects of Perinatal InterventionR56HL143459 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI ALEXANDER, BARBARA T · 2018 to 2018
$300k
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL143459HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R56HL143459HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) T32HL105324HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM104357HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM121334NHLBI NIH HHS P01 HL051971NHLBI NIH HHS R01 HL143459NHLBI NIH HHS R56 HL143459NHLBI NIH HHS T32 HL105324NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20 GM121334
6 · The paper itself

Abstract

Stimulation of soluble guanylate cyclase (sGC) improves fetal growth at gestational

Indexed as

AnimalsBlood PressureEnzyme ActivatorsFemaleFetal Growth RetardationPlacentaPlacental InsufficiencyPregnancyPyrazolesPyrimidinesRatsRats, Sprague-DawleySoluble Guanylyl CyclaseVascular ResistanceEnzyme ActivatorsPyrazolesPyrimidinesriociguatSoluble Guanylyl Cyclaseblood pressurecardiac dysfunctionintrauterine growth restrictionplacental ischemiasoluble guanylate cyclase

Identifiers

PMID33739156
PMCPMC8428889
OpenAlexW3137826628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.