ArticleChemical reviews2021
Recent Advances in Enantioselective Pd-Catalyzed Allylic Substitution: From Design to Applications.
Article in Chemical reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
91 citing papers in PubMed, 562 citations in OpenAlex.
- Orthogonal nucleophile-ordered assembly for modular access to enantiopure 1,2-amino alcohols.Nature chemistry · 2026Article
- Article
- The Catalytic Asymmetric Alkylation of Olefins with Alcohol Derivatives.Journal of the American Chemical Society · 2026Article
- Copper-catalyzed enantioselective allylation of cyclic anhydrides for generation of multiple chiral centers.Nature communications · 2026Article
- Palladium(0)-Catalysed Stereoselective Synthesis of Unsaturated Aryl β-Molecules (Basel, Switzerland) · 2026Article
- Palladium-Catalyzed Intramolecular Asymmetric Allylic Amidation: A General Route to 5-Substituted Chiral Oxazolines.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Palladium-catalyzed asymmetric carbofluorination ofChemical communications (Cambridge, England) · 2026Article
- 3-Azetidinylpiperidine-4-alkylidenemalononitrile and Related Building Blocks.Organic letters · 2026Article
- Dynamic palladium catalysis enables chiral amplification toward acyclic Schiff base atropisomers.Nature communications · 2026Article
- Applying asymmetric-waveform alternating current in nickel-catalyzed asymmetric reductive cross-coupling.Nature communications · 2026Article
- Enantioselective Pd-Catalyzed Electrochemical Dearomative Allylation of Tropones: Construction of All-C Quaternary Stereocenters.Organic letters · 2026Article
- Article
- Halogen bonding-induced 1,3-carbohydroxylation of allyl carboxylatesChemical science · 2026Article
- Fluoride-Transfer Asymmetric Allylic Alkylation Enables Regiodivergent, Stereoselective Cross-Electrophile Coupling.Angewandte Chemie (International ed. in English) · 2026Article
- Enantioselective Trifunctionalization of Terminal Alkynes.Journal of the American Chemical Society · 2025Article
- General Light-Induced Pd-Catalyzed Allylic C-H Alkylation of Internal Alkenes: Direct Access to Tertiary and Quaternary Carbon Centers.Journal of the American Chemical Society · 2025Article
- Cu-Catalyzed Three-Component Carbofunctionalization of 1,3-Dienes.ACS catalysis · 2025Article
- Directing Effects of Silyl and Germyl Groups in Transition-Metal-Catalyzed Allylic Substitution.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Review
- Metal-Free Catalytic Synthesis ofACS omega · 2025Article
- C(spJournal of the American Chemical Society · 2025Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This Review compiles the evolution, mechanistic understanding, and more recent advances in enantioselective Pd-catalyzed allylic substitution and decarboxylative and oxidative allylic substitutions. For each reaction, the catalytic data, as well as examples of their application to the synthesis of more complex molecules, are collected. Sections in which we discuss key mechanistic aspects for high selectivity and a comparison with other metals (with advantages and disadvantages) are also included. For Pd-catalyzed asymmetric allylic substitution, the catalytic data are grouped according to the type of nucleophile employed. Because of the prominent position of the use of stabilized carbon nucleophiles and heteronucleophiles, many chiral ligands have been developed. To better compare the results, they are presented grouped by ligand types. Pd-catalyzed asymmetric decarboxylative reactions are mainly promoted by PHOX or Trost ligands, which justifies organizing this section in chronological order. For asymmetric oxidative allylic substitution the results are grouped according to the type of nucleophile used.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.