Evidence map›Paper›PMID 33738621›Full record

ReviewCurrent allergy and asthma reports2021

Skin Testing for Penicillin Allergy: a Review of the Literature.

Tracy Zembles, Michelle Mitchell, Waleed Alqurashi, Mariana Castells, Elizabeth J Phillips, David Vyles

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Treatment ofAntibiotics (Basel, Switzerland) · 2023
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Tracy ZemblesDepartment of Enterprise Safety, Children's Wisconsin, Milwaukee, WI, USA.ORCID 0000-0003-3727-7970
Michelle MitchellDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Waleed AlqurashiDepartment of Pediatrics and Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Mariana CastellsDivison of Rheumatology, Immunology, and Allergy, Harvard Medical School, Harvard University, and Brigham and Women's Hospital, Boston, MA, USA.
Elizabeth J PhillipsDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
David VylesDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA. dvyles@mcw.edu.
Medical College of Wisconsin · USBrigham and Women's Hospital · USChildren's Hospital of Wisconsin · USUniversity of Ottawa · CAVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewSelf-reported penicillin allergies are frequently reported, though more than 95% of those are not truly allergic when challenged. These patients are more likely to receive alternative antibiotic regimens resulting in the use of broad-spectrum antibiotics that may be less effective, more toxic, and/or more expensive than preferred agents. Given the significant burden on patient outcomes and the healthcare system, the ability to reconcile an allergy and broaden future antibiotic options is essential. RECENT

findingsThis is a narrative review describing risk stratification for penicillin skin testing, practical advice for implementation, and future directions. A summary of studies within the last 5 years is provided. The trend over the past several years has been to offer oral drug challenges to low-risk patients and skin testing to high-risk patients with a reported penicillin allergy. This review provides support for risk stratification assessment of reported penicillin allergy to optimize antibiotic use and prevent emergence of antimicrobial resistance.

Indexed as

Drug HypersensitivityPenicillinsAnti-Bacterial AgentsHumansSkin TestsAnti-Bacterial AgentsPenicillinsAllergyPenicillinSkin testing

Identifiers

PMID33738621
OpenAlexW3137042514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.