Evidence map›Paper›PMID 33738599›Full record

ArticleEuropean radiology2021

Indication of the prognosis of pulmonary hypertension by using CMR function parameters.

Wen Ren, Jing-Jing Guo, Fan Yang, Zhen-Wen Yang, Tie-Lian Yu, Yuan-Lin Deng, Zhang Zhang, Dong Li

Abstract read
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In one paragraph

Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Wen Ren *Department of Radiology, The Affiliated Suzhou Hospital of Nanjing Medical University, 242 Guangji Road, Suzhou, 215008, Jiangsu, China.
Jing-Jing Guo *Department of Radiology, Tianjin Huanhu Hospital, 6 Jizhao Road, Tianjin, 300350, China.
Fan Yang *Department of Radiology, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China.
Zhen-Wen YangDepartment of Cardiology, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China.
Tie-Lian YuDepartment of Radiology, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China.
Yuan-Lin DengDepartment of Radiology, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China.
Zhang ZhangDepartment of Radiology, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China. filea1249@sina.com.
Dong LiDepartment of Radiology, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China. dr_lidong@163.com.
Tianjin Medical University General Hospital · CNNanjing Medical University · CNTianjin Huanhu Hospital · CN

Funding

National Natural Science Youth Science Fund Project Foundation of China 81301217Tianjin Key Project of Applied Basic and Frontier Technology Research Program 14JCZDJC57000
6 · The paper itself

Abstract

objectiveThis study aimed to compare the cardiac function among different sub-types of pulmonary hypertension (PH) and to explore the independent predictors of major adverse cardiovascular events (MACE).

methodsEighty-seven PH patients diagnosed by right heart catheterization (RHC) were recruited. Patients underwent cardiac magnetic resonance (CMR) and RHC examination within 2 weeks. The CMR images were analyzed to calculate the cardiac functional parameters including right ventricle (RV) and left ventricle (LV) end-diastolic volume index (EDVI), end-systolic volume index (ESVI), stroke volume index (SVI), ejection fraction (EF), tricuspid annular plane systolic excursion (TAPSE), and myocardial mass (MM). The median follow-up time was 46.5 months (interquartile range: 26-65.5 months), and the endpoints were the occurrence of MACE.

resultsRVEDVI, LVEDVI, and LVESVI were higher in congenital heart disease-related PH (CHD-PH) than in other sub-types (p < 0.05). RVMM, RVSVI, and RVCI were highest in CHD-PH. There was no significant difference in the prognosis among different sub-types (p > 0.05). Comparing with the non-MACE group, RVEF, TAPSE, and LVSVI significantly decreased in the MACE group, while the RVESVI significantly increased (p < 0.05). TAPSE ≤ 15.65 mm and LVSVI ≤ 30.27 mL/m

conclusionCHD-PH had a higher RV function reserve but lowest LVEF comparing to other subgroups. TAPSE and LVSVI could contribute to the prediction of MACE in PH patients. KEY POINTS: • CMR imaging is a noninvasive and accurate tool to assess ventricular function. • CHD-PH had higher RV function reserve but lowest LVEF. • TAPSE and LVSVI could contribute to the prediction of MACE in PH patients.

Indexed as

Hypertension, PulmonaryVentricular Dysfunction, RightHumansMagnetic Resonance SpectroscopyPrognosisStroke VolumeVentricular Function, RightFollow-up studiesHeart defects, congenitalHypertension, pulmonaryMagnetic resonance imagingPrognosis

Identifiers

PMID33738599
OpenAlexW3138903369

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.