Evidence map›Paper›PMID 33738565›Full record

ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Non-aesthetic uses of botulinum toxin in the head and neck.

Natalie Anne Watson, Zohaib Siddiqui, Benjamin John Miller, Yakubu Karagama, Nicholas Gibbins

Abstract readReview
PubMed Publisher
In one paragraph

Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. The effect of botulinum toxin in the masticatory and constrictor musculature of the pharynx as an option in the treatment of obstructive sleep apnea: a case report.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  2. Retrograde Cricopharyngeal Dysfunction: A Review.Journal of clinical medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Natalie Anne WatsonDepartment of Otolaryngology, Guy's and St Thomas' NHS Foundation Trust, London, UK. nataliewatson@doctors.org.uk.ORCID http://orcid.org/0000-0002-0839-3094
Zohaib SiddiquiDepartment of Otolaryngology, Lewisham and Greenwich NHS Trust, Lewisham High Street, London, SE13 6LH, UK.
Benjamin John MillerDepartment of Otolaryngology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Yakubu KaragamaDepartment of Otolaryngology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Nicholas GibbinsDepartment of Otolaryngology, Lewisham and Greenwich NHS Trust, Lewisham High Street, London, SE13 6LH, UK.
Guy's and St Thomas' NHS Foundation Trust · GBLewisham and Greenwich NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe use of botulinum toxin in the specialty of aesthetic surgery in the head and neck is well known. However, it has also been used for other conditions affecting the head and neck, and in recent years its use, as well as the number of relevant applications, has expanded enormously. REVIEW: This article presents a summary of the current range of uses in the laryngeal, pharyngeal, cervical, oromandibular and facial muscles and salivary glands. We highlight particular conditions focusing on dystonia (laryngeal, craniocervical, oromandibular and cervical), multiple system atrophy, migraines, facial nerve palsy, post-laryngectomy, cricopharyngeal dysphagia, Zenker's diverticulum, retrograde cricopharyngeal dysfunction disorder, sialorrhea and gustatory sweating (Frey's syndrome).

conclusionThis article should aid the ear, nose and throat surgeon garner knowledge about the range of uses for botulinum toxin in the head and neck.

Indexed as

Botulinum Toxins, Type APharyngeal DiseasesSweating, GustatoryHeadHumansNeckBotulinum Toxins, Type ABotulinum toxin injectionCricopharyngeal dysphagiaDystoniaMigraineSpasmodic dysphonia

Identifiers

PMID33738565
OpenAlexW3135915444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.