Evidence map›Paper›PMID 33738519›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

Image quality and lesion detectability in low-dose pediatric

Yu-Mo Zhao, Ying-He Li, Tao Chen, Wei-Guang Zhang, Lin-Hao Wang, Jiatai Feng, Chenwei Li, Xu Zhang, Wei Fan, Ying-Ying Hu

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 93 citations in OpenAlex.

  1. An artificial intelligence-driven image quality assessment system for whole-body [European journal of nuclear medicine and molecular imaging · 2023
    Trial
  2. Review
  3. Optimization of Administered Activity forWorld journal of nuclear medicine · 2026
    Article
  4. Article
  5. PET scout: A valuable technology in pediatricEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  6. Article
  7. Lung lesion detectability on images obtained from decimated and CNN-based denoised [European journal of nuclear medicine and molecular imaging · 2025
    Article
  8. Lymphoma Therapy Response Assessment with Low-Dose [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  9. A scoping review on potential of novel developments in fever of unknown origin and inflammation of unknown origin: long-axial-field-of-view positron emission tomography/computed tomography and novel radiotracers.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2025
    Article
  10. Assessment of reducedAnnals of nuclear medicine · 2025
    Article
  11. Article
  12. Diagnostic accuracy in NSCLC lymph node staging with Total-Body and conventional PET/CT.European journal of nuclear medicine and molecular imaging · 2025
    Article
  13. A low-dose protocol in pediatricAnnals of nuclear medicine · 2025
    Article
  14. EJNMMI physics · 2025
    Article
  15. Role of Total Body PET/CT in Inflammatory Disorders.Seminars in nuclear medicine · 2025
    Review
  16. Article
  17. Sedation-free pediatric [European journal of nuclear medicine and molecular imaging · 2024
    Article
  18. Article
  19. Review
  20. Dose Reduction in Pediatric Oncology Patients with Delayed Total-Body [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yu-Mo Zhao *State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China.
Ying-He Li *State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China.
Tao ChenState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China.
Wei-Guang ZhangState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China.
Lin-Hao WangState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China.
Jiatai FengCentral research institute, United Imaging Healthcare, Shanghai, China.
Chenwei LiCentral research institute, United Imaging Healthcare, Shanghai, China.
Xu ZhangState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China. zhangx2@sysucc.org.cn.
Wei FanState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China. fanwei@sysucc.org.cn.
Ying-Ying HuState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China. huyy@sysucc.org.cn.
State Key Laboratory of Oncology in South ChinaSun Yat-sen University · CNSun Yat-sen University Cancer Center · CNUnited Imaging Healthcare (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the effects of dose reduction on image quality and lesion detectability of oncological

methodsA total of 33 pediatric patients (weight 8.5-58.5 kg; age 0.8-17.6 years) underwent total-body PET/CT using uEXPLORER scanner with an

resultsOur analysis shows that sufficient subjective image quality and lesion conspicuity could be maintained down to 1/30th (0.12 MBq/kg) of the administered dose of

conclusionThe total-body PET/CT might significantly decrease the administered dose upon maintaining the image quality and diagnostic performance of micro-lesions in pediatric patients. Data suggests that using total-body PET/CT, optimal image quality could be achieved with an administered dose-reduction down to 1/10-dose (0.37 MBq/kg).

Indexed as

Fluorodeoxyglucose F18NeoplasmsAdolescentChildChild, PreschoolHumansInfantPositron-Emission TomographyPositron Emission Tomography Computed TomographyRetrospective StudiesFluorodeoxyglucose F1818F-FDGLow-dosePediatricTotal-body PET/CT

Identifiers

PMID33738519
OpenAlexW3130779112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.