Evidence map›Paper›PMID 33738469›Full record

ArticleAmerican journal of epidemiology2021

Are Recent Cohorts Getting Worse? Trends in US Adult Physiological Status, Mental Health, and Health Behaviors Across a Century of Birth Cohorts.

Hui Zheng, Paola Echave

Abstract read
In one paragraph

Article in American journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
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  13. Younger Older Americans and Sarcopenic Obesity: The Moderating Role of Living Alone.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  14. Cohort Differences in Physical Health and Disability in the United States and Europe.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
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  20. Cohort Trends in the Burden of Multiple Chronic Conditions Among Aging U.S. Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Hui Zheng
Paola Echave

Funding

Institute for Population ResearchP2CHD058484 · NICHD · OHIO STATE UNIVERSITY · PI HAYFORD, SARAH R · 2014 to 2023
$5.0M
A Semi-parametric Approach to Mitigate Lagged Selection Bias in Trend StudiesR03SH000046 · SH · OHIO STATE UNIVERSITY · PI ZHENG, HUI · 2016 to 2017
$148k
Population Heterogeneity in the Effects of Obesity on Mortality over the Life CourseR03AG053463 · NIA · OHIO STATE UNIVERSITY · PI ZHENG, HUI · 2017 to 2018
$148k
NCHS CDC HHS R03 SH000046NIA NIH HHS R03 AG053463NICHD NIH HHS P2C HD058484
6 · The paper itself

Abstract

Morbidity and mortality have been increasing among middle-aged and young-old Americans since the turn of the century. We investigated whether these unfavorable trends extend to younger cohorts and their underlying physiological, psychological, and behavioral mechanisms. Applying generalized linear mixed-effects models to data from 62,833 adults from the National Health and Nutrition Examination Surveys (1988-2016) and 625,221 adults from the National Health Interview Surveys (1997-2018), we found that for all sex and racial groups, physiological dysregulation has increased continuously from Baby Boomers through late-Generation X and Generation Y. The magnitude of the increase was higher for White men than for other groups, while Black men had a steepest increase in low urinary albumin (a marker of chronic inflammation). In addition, Whites underwent distinctive increases in anxiety, depression, and heavy drinking, and they had a higher level than Blacks and Hispanics of smoking and drug use in recent cohorts. Smoking is not responsible for the increasing physiological dysregulation across cohorts. The obesity epidemic contributes to the increase in metabolic syndrome but not in low urinary albumin. The worsening physiological and mental health profiles among younger generations imply a challenging morbidity and mortality prospect for the United States, one that might be particularly inauspicious for Whites.

Indexed as

Health StatusAdultAgedAged, 80 and overCohort StudiesFemaleHealth BehaviorHumansMaleMental HealthMiddle AgedNutrition SurveysSex FactorsUnited StatesYoung Adultcohort analysisgender disparitieshealth behaviorsmental healthmorbidity and mortalityobesityphysiological statusracial disparities

Identifiers

PMID33738469
PMCPMC8799895

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.