Evidence map›Paper›PMID 33738350›Full record

ArticleCirculation reports2021

Exosome miR-501-3p Elevation Contributes to Progression of Vascular Stiffness.

Kensuke Toyama, Michiya Igase, Joshua M Spin, Yasunori Abe, Amarsanaa Javkhlant, Yoko Okada, Markus U Wagenhäuser, Hubert Schelzig, Philip S Tsao, Masaki Mogi

Open access · diamondAbstract read
In one paragraph

Article in Circulation reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Abdominal aortic aneurysm progression: A review of preclinical and clinical data.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Review
  3. The Role of miR-501-3p in Abdominal Aortic Aneurysm Progression: A Pilot Study.Journal of cardiovascular translational research · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Kensuke ToyamaDepartment of Pharmacology, Ehime University Graduate School of Medicine Toon Japan.
Michiya IgaseDepartment of Anti-aging Medicine, Ehime University Graduate School of Medicine Toon Japan.
Joshua M SpinVA Palo Alto Health Care System Palo Alto, CA USA.
Yasunori AbeDepartment of Pharmacology, Ehime University Graduate School of Medicine Toon Japan.
Amarsanaa JavkhlantDepartment of Pharmacology, Ehime University Graduate School of Medicine Toon Japan.
Yoko OkadaDepartment of Anti-aging Medicine, Ehime University Graduate School of Medicine Toon Japan.
Markus U WagenhäuserDepartment of Vascular and Endovascular Surgery, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf Germany.
Hubert SchelzigDepartment of Vascular and Endovascular Surgery, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf Germany.
Philip S TsaoVA Palo Alto Health Care System Palo Alto, CA USA.
Masaki MogiDepartment of Pharmacology, Ehime University Graduate School of Medicine Toon Japan.
Ehime University · JPDüsseldorf University Hospital · DEStanford University · USVA Palo Alto Health Care System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Arterial stiffnessArteriosclerosisExosomemiR-501-3p

Identifiers

PMID33738350
PMCPMC7956882
OpenAlexW3132654433

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.