Evidence map›Paper›PMID 33738327›Full record

ArticleMolecular therapy. Methods & clinical development2021

Improved diabetic wound healing by LFcinB is associated with relevant changes in the skin immune response and microbiota.

Michelle V Mouritzen, Marija Petkovic, Katrine Qvist, Steen S Poulsen, Susana Alarico, Ermelindo C Leal, Louise T Dalgaard, Nuno Empadinhas, Eugenia Carvalho, Håvard Jenssen

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Michelle V MouritzenDepartment of Science and Environment, Roskilde University, Roskilde, Denmark.
Marija PetkovicDepartment of Science and Environment, Roskilde University, Roskilde, Denmark.
Katrine QvistDepartment of Science and Environment, Roskilde University, Roskilde, Denmark.
Steen S PoulsenDepartment of Biomedical Science, University of Copenhagen, Copenhagen, Denmark.
Susana AlaricoCenter for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Ermelindo C LealCenter for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Louise T DalgaardDepartment of Science and Environment, Roskilde University, Roskilde, Denmark.
Nuno EmpadinhasCenter for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Eugenia CarvalhoCenter for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Håvard JenssenDepartment of Science and Environment, Roskilde University, Roskilde, Denmark.
Roskilde University · DKUniversity of Coimbra · PTUniversity of Copenhagen · DK

Funding

The Role of the Mitochondrion in the Metabolic Stress Response to Burn TraumaP20GM109096 · NIGMS · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI PORTER, CRAIG · 2016 to 2025
$20.7M
RESOURCE CORE 3: ANALYTICAL COREP30AG028718 · NIA · UNIV OF ARKANSAS FOR MED SCIS · PI WEI, JEANNE Y · 2011 to 2015
$5.1M
STUDIES IN MATHEMATICS AND STATISTICSZ01CT000024 · CIT · COMPUTER RESEARCH AND TECHNOLOGY · PI WEISS, GEORGE H · 1985 to 2008
$408k
Intramural NIH HHS Z01 CT000024NIA NIH HHS P30 AG028718NIGMS NIH HHS P20 GM109096
6 · The paper itself

Abstract

Bovine lactoferricin (LFcinB) has antimicrobial and immunomodulatory properties; however, the effects on diabetic wound healing remain poorly understood. The wound healing potential of LFcinB was investigated with

Indexed as

bacterial diversitybovine lactoferricincollagen depositiondiabetesimmunomodulationinflammatory cytokinesmacrophage polarizationwound healing

Identifiers

PMID33738327
PMCPMC7940703
OpenAlexW3132487368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.