Evidence map›Paper›PMID 33738263›Full record

ArticleJournal of multimorbidity and comorbidity

Trends in the magnitude of chronic conditions in patients hospitalized with a first acute myocardial infarction.

Mayra Tisminetzky, Ruben Miozzo, Joel M Gore, Jerry H Gurwitz, Darleen Lessard, Jorge Yarzebski, Edgard Granillo, Hawa O Abu, Robert J Goldberg

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of multimorbidity and comorbidity. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mayra TisminetzkyMeyers Primary Care Institute, Worcester, MA, USA.ORCID 0000-0002-8557-2029
Ruben MiozzoJohns Hopkins Bloomberg School of Public Health Baltimore, MD, USA.
Joel M GoreDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Jerry H GurwitzMeyers Primary Care Institute, Worcester, MA, USA.
Darleen LessardDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Jorge YarzebskiDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Edgard GranilloDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Hawa O AbuDivision of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester MA, USA.
Robert J GoldbergMeyers Primary Care Institute, Worcester, MA, USA.
University of Massachusetts Chan Medical School · USJohns Hopkins University · US

Funding

Preparing For What Is Next With Aducanumab In Real World SettingsR33AG057806 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Christopher Barrett Bowling, Ana Roman Quinones · 2018 to 2026
$9.0M
WORCHESTER HEART ATTACK COMMUNITY SURVEILLANCE STUDYR01HL035434 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GOLDBERG, ROBERT JOEL · 1987 to 2014
$7.4M
TRACE-COREU01HL105268 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIEFE, CATARINA I. · 2010 to 2013
$5.8M
Multimorbidity and Treatment-Related Outcomes in Older Heart Failure PatientsR01AG062630 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI TISMINETZKY, MAYRA S. · 2019 to 2022
$2.4M
NHLBI NIH HHS R01 HL035434NHLBI NIH HHS U01 HL105268NIA NIH HHS R01 AG062630NIA NIH HHS R33 AG057806
6 · The paper itself

Abstract

backgroundAmong adults with heart disease, there is a high prevalence of concomitant chronic medical conditions. We studied patients with a first acute myocardial infarction to describe: sample population characteristics; trends of the most prevalent pairs of chronic conditions; and differences in hospital management according to burden of these morbidities. METHODS AND

resultsPatients (n = 1,564) hospitalized with an incident AMI at the 3 major medical centers in central Massachusetts during 2005, 2011, and 2015 comprised the study population. Hospital medical records were reviewed to identify 11 more prevalent chronic conditions. The median age of this population was 68 years and 56% were men. The median number of previously diagnosed chronic conditions was 2. Patients hospitalized during 2015 were more likely to be younger than those hospitalized in the earliest study cohorts. The most common pairs of chronic conditions for those hospitalized in 2005 were: anemia-chronic kidney disease (31%), chronic kidney disease-heart failure (30%), and stroke-atrial fibrillation (27%). Among patients hospitalized during 2011, chronic kidney disease-heart failure (29%), hypertension-hyperlipidemia (27%), and hypertension-diabetes (27%) were the most common pairs whereas hypertension-hyperlipidemia (43%), diabetes-heart failure (30%), and chronic kidney disease-diabetes (23%) were the most frequent pairs recorded in 2015. There was a significant decrease in the odds of undergoing cardiac catheterization and a percutaneous coronary intervention in those with higher chronic disease burden in the most recent as compared to earliest study years.

conclusionsOur findings highlight the magnitude of chronic conditions in patients with AMI and the challenges of caring for this vulnerable population.

Indexed as

comorbiditiesMultimorbiditymyocardial infarction

Identifiers

PMID33738263
PMCPMC7934031
OpenAlexW3134149456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.