Evidence map›Paper›PMID 33738243›Full record

ArticleFrontiers in oncology2020

Unbiased Phenotype-Based Screen Identifies Therapeutic Agents Selective for Metastatic Prostate Cancer.

Ivy Chung, Kun Zhou, Courtney Barrows, Jacqueline Banyard, Arianne Wilson, Nathan Rummel, Atsushi Mizokami, Sudipta Basu, Poulomi Sengupta, Badaruddin Shaikh and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Ivy ChungVascular Biology Program, Boston Children's Hospital, Boston, MA, United States.
Kun ZhouVascular Biology Program, Boston Children's Hospital, Boston, MA, United States.
Courtney BarrowsVascular Biology Program, Boston Children's Hospital, Boston, MA, United States.
Jacqueline BanyardVascular Biology Program, Boston Children's Hospital, Boston, MA, United States.
Arianne WilsonVascular Biology Program, Boston Children's Hospital, Boston, MA, United States.
Nathan RummelCenter for Veterinary Medicine, U.S. Food and Drug Administration, Washington, DC, United States.
Atsushi MizokamiDepartment of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.
Sudipta BasuLaboratory for Nanomedicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Poulomi SenguptaLaboratory for Nanomedicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Badaruddin ShaikhCenter for Veterinary Medicine, U.S. Food and Drug Administration, Washington, DC, United States.
Shiladitya SenguptaLaboratory for Nanomedicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Diane R BielenbergVascular Biology Program, Boston Children's Hospital, Boston, MA, United States.
Bruce R ZetterVascular Biology Program, Boston Children's Hospital, Boston, MA, United States.
Boston Children's Hospital · USBrigham and Women's Hospital · USUnited States Food and Drug Administration · USHarvard University · USKanazawa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In American men, prostate cancer is the second leading cause of cancer-related death. Dissemination of prostate cancer cells to distant organs significantly worsens patients' prognosis, and currently there are no effective treatment options that can cure advanced-stage prostate cancer. In an effort to identify compounds selective for metastatic prostate cancer cells over benign prostate cancer cells or normal prostate epithelial cells, we applied a phenotype-based

Indexed as

bonecarcinomadrug-screenmetastasisprostate

Identifiers

PMID33738243
PMCPMC7962607
OpenAlexW3134573951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.