ReviewThe Japanese dental science review2021
Molecular biological findings of ameloblastoma.
Review in The Japanese dental science review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 45 citations in OpenAlex.
- Implications of ADP-Ribosylation Factor-Like Protein 4C (ARL4C) in Human Neoplasia With Special Emphasis on Ameloblastoma: A Scoping Review.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026Article
- Overexpression of FGFR2 in Mandibular Ameloblastoma Is Potentially Associated with Gene Amplification and Deletion.International journal of molecular sciences · 2026Article
- Review
- Spontaneous Bone Regeneration followed by Segmental Resection of Mandibular Unicystic Ameloblastoma with Primary Reconstruction in 12-Year-Old Girl: A Case Report.World journal of plastic surgery · 2026Article
- Bibliometric insights into molecular and bioinformatic research trends on ameloblastoma.Discover oncology · 2025Article
- Ameloblastoma of the Maxilla With Distant Metastases to the Lungs: A Case Report and Literature Review.Cureus · 2024Article
- Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma.International journal of oral science · 2024Article
- Malignant transformation of primary ameloblastoma of skull: case report and review of current literature.Frontiers in oncology · 2024Article
- Article
- Review
- Scalloped border as a possible diagnostic aid for differentiating jaw lesions: A pictorial essay.Imaging science in dentistry · 2022Article
- Review
- FOSL1 promotes tumor growth and invasion in ameloblastoma.Frontiers in oncology · 2022Article
- CDC7 Expression in Selected Odontogenic Tumors.International journal of dentistry · 2022Article
- [Molecular basis of ameloblastoma pathogenesis: A review].Revista cientifica odontologica (Universidad Cientifica del Sur)Review
- Alpha-tocopherol Levels in Predicting the Biological Behaviour of Ameloblastoma - A Comparative Study.Annals of maxillofacial surgeryArticle
- Analysis of local aggressiveness and malignancy transformation potential of ameloblastoma through osteopontin and CD10 expression (Immunohistochemical research).Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ameloblastoma is benign odontogenic tumours that mainly occur in the jawbone. This tumour induces aggressive invasion into the surrounding bone and has a high recurrence rate after surgery. Therefore, mandibular resection is performed in many patients with this tumour, causing aesthetic and functional problems. It is necessary to develop a novel treatment strategy for ameloblastoma, but there are currently no innovative treatments. Although our understanding of the molecular biological mechanisms of ameloblastoma is still insufficient, there have been many recent reports of new molecular biological findings on ameloblastoma. Therefore, bioactive factors that have potential for novel therapeutic methods, such as molecular targeted therapy, have been discovered in ameloblastoma. In this review, we summarize the molecular biological findings of ameloblastoma reported over several decades, focusing on factors involved in invasion into surrounding tissues and disease-specific gene mutations. We also mention the effect of the interaction between tumour cells and stromal components in ameloblastoma on tumour development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.