ArticleTherapeutic advances in neurological disorders2021
The value of qualitative muscle MRI in the diagnostic procedures of myopathies: a biopsy-controlled study in 191 patients.
Article in Therapeutic advances in neurological disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- [Expert recommendations for magnetic resonance imaging of muscle disorders].Radiologie (Heidelberg, Germany) · 2024Guideline
- Dermatomyositis masking late onset Pompe disease in a patient with proximal muscle weakness.Journal of neuromuscular diseases · 2026Article
- MRI image segmentation of the major lower leg muscles using deep learning: application in biomechanical analysis.Medical & biological engineering & computing · 2026Article
- Magnetic resonance imaging applications to amyotrophic lateral sclerosis beyond the central nervous system.Frontiers in neurology · 2026Review
- Parkinson's disease-associated camptocormia: biopsy-confirmed focal myositis and treatment options.Journal of neurology · 2025Article
- [Expert recommendations for magnetic resonance imaging of muscle disorders].Der Nervenarzt · 2024Review
- The central pattern of weakness of ALS: Morphological correlates in whole-body muscle MRI.Annals of clinical and translational neurology · 2024Article
- Misdiagnosis of polymyositis in a young female patient with occult limb-girdle muscular dystrophy.Rheumatology advances in practice · 2023Article
- Does MIS-TLIF or TLIF result in better pedicle screw placement accuracy and clinical outcomes with navigation guidance?BMC musculoskeletal disorders · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThe role of muscle magnetic resonance imaging (MRI) in the diagnostic procedures of myopathies is still controversially discussed. The current study was designed to analyze the status of qualitative muscle MRI, electromyography (EMG), and muscle biopsy in different cases of clinically suspected myopathy.
methodsA total of 191 patients (male:
resultsDiagnostic findings according to biopsy results and genetic testing were as follow: non-inflammatory myopathy: DISCUSSION AND
conclusionThe study provides guidance in the definition of the impact of muscle MRI in suspected myopathy: despite being an important diagnostic tool, qualitative MRI findings could not distinguish different types of neuromuscular diagnostic groups in comparison with the gold standard histopathologic diagnosis and/or genetic testing. The results suggest that neither muscle edema nor gadolinium enhancement are able to secure a diagnosis of myositis. The current results do not support qualitative MRI as aiding in the diagnostic distinction of various myopathies. Quantitative muscle MRI is, however, useful in the diagnostic procedure of a suspected neuromuscular disease, especially with regard to assessing progression of a chronic myopathy by quantification of the degree of atrophy and fatty replacement and in exploring patterns of muscle group involvements in certain genetic myopathies.
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