Evidence map›Paper›PMID 33737939›Full record

ArticleFrontiers in immunology2021

Direct LC-MS/MS Analysis of Extra- and Intracellular Glycerophosphoinositol in Model Cancer Cell Lines.

Ana Margarida Campos, Genoveffa Nuzzo, Alessia Varone, Paola Italiani, Diana Boraschi, Daniela Corda, Angelo Fontana

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ana Margarida CamposConsiglio Nazionale delle Ricerche, Institute of Biomolecular Chemistry, Pozzuoli, Italy.
Genoveffa NuzzoConsiglio Nazionale delle Ricerche, Institute of Biomolecular Chemistry, Pozzuoli, Italy.
Alessia VaroneConsiglio Nazionale delle Ricerche, Institute of Biochemistry and Cell Biology, Naples, Italy.
Paola ItalianiConsiglio Nazionale delle Ricerche, Institute of Biochemistry and Cell Biology, Naples, Italy.
Diana BoraschiConsiglio Nazionale delle Ricerche, Institute of Biochemistry and Cell Biology, Naples, Italy.
Daniela CordaConsiglio Nazionale delle Ricerche, Institute of Biochemistry and Cell Biology, Naples, Italy.
Angelo FontanaConsiglio Nazionale delle Ricerche, Institute of Biomolecular Chemistry, Pozzuoli, Italy.
National Research Council · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycerophosphoinositols (GPIs) are water-soluble bioactive phospholipid derivatives of increasing interest as intracellular and paracrine mediators of eukaryotic cell functions. The most representative compound of the family is glycerophosphoinositol (GroPIns), an ubiquitous component of mammalian cells that participates in cell proliferation, cell survival and cell response to stimuli. Levels and activity of this compound vary among cell types and deciphering these functions requires accurate measurements in

Indexed as

Cell LineCell Line, TumorChromatography, LiquidExtracellular SpaceHumansInositol PhosphatesIntracellular SpacePC-3 CellsReproducibility of ResultsSolid Phase ExtractionTandem Mass SpectrometryglycerylphosphoinositolInositol Phosphatesautocrine and paracrine mechanismcancerinflammationlipid metabolismmass spectrometrysecond messengersolid phase extraction

Identifiers

PMID33737939
PMCPMC7960645
OpenAlexW3134425486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.