Evidence map›Paper›PMID 33737928›Full record

ArticleFrontiers in immunology2021

Immunoinformatics Design of Multi-Epitope Peptide-Based Vaccine Against

Rodrigo C O Sanches, Sandeep Tiwari, Laís C G Ferreira, Flávio M Oliveira, Marcelo D Lopes, Maria J F Passos, Eduardo H B Maia, Alex G Taranto, Rodrigo Kato, Vasco A C Azevedo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 155 citations in OpenAlex.

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  18. Design of a Multi-Epitope Vaccine Based onInternational journal of molecular sciences · 2025
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  19. Review
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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Rodrigo C O SanchesLaboratório de Biologia Molecular, Universidade Federal de São João del-Rei, Divinópolis, Brazil.
Sandeep TiwariPrograma de Pós-Graduação em Bioinformática, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Laís C G FerreiraLaboratório de Biologia Molecular, Universidade Federal de São João del-Rei, Divinópolis, Brazil.
Flávio M OliveiraLaboratório de Biologia Molecular, Universidade Federal de São João del-Rei, Divinópolis, Brazil.
Marcelo D LopesLaboratório de Biologia Molecular, Universidade Federal de São João del-Rei, Divinópolis, Brazil.
Maria J F PassosLaboratório de Biologia Molecular, Universidade Federal de São João del-Rei, Divinópolis, Brazil.
Eduardo H B MaiaLaboratório de Química Farmacêutica Medicinal, Universidade Federal de São João del-Rei, Divinópolis, Brazil.
Alex G TarantoLaboratório de Química Farmacêutica Medicinal, Universidade Federal de São João del-Rei, Divinópolis, Brazil.
Rodrigo KatoPrograma de Pós-Graduação em Bioinformática, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Vasco A C AzevedoPrograma de Pós-Graduação em Bioinformática, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Debora O LopesLaboratório de Biologia Molecular, Universidade Federal de São João del-Rei, Divinópolis, Brazil.
Federal University of São João del-Rei · BRUniversidade Federal de Minas Gerais · BRFederal Center for Technological Education of Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schistosomiasis remains a serious health issue nowadays for an estimated one billion people in 79 countries around the world. Great efforts have been made to identify good vaccine candidates during the last decades, but only three molecules reached clinical trials so far. The reverse vaccinology approach has become an attractive option for vaccine design, especially regarding parasites like

Indexed as

AnimalsAntigens, HelminthB-LymphocytesComputational BiologyEpitope MappingHistocompatibility Antigens Class IHistocompatibility Antigens Class IIHumansImmunity, CellularImmunity, HumoralImmunodominant EpitopesInterferon-gammaLymphocyte ActivationMedical InformaticsMembrane ProteinsMolecular Docking SimulationAntigens, HelminthHistocompatibility Antigens Class IHistocompatibility Antigens Class IIImmunodominant EpitopesInterferon-gammaMembrane ProteinsRecombinant Fusion ProteinsToll-Like Receptor 4VaccinesVaccines, Subunitbioinformaticschimeric antigenimmunoinformaticsmulti-epitope vaccineschistosomiasistransmembrane proteins

Identifiers

PMID33737928
PMCPMC7961083
OpenAlexW3135817348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.