Trial reportFrontiers in immunology2021
Cervicovaginal Immune Activation in Zambian Women With Female Genital Schistosomiasis.
Open access · goldAbstract readClinical Trial
In one paragraph
Trial report in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Association of female genital schistosomiasis and human papillomavirus and cervical pre-cancer: a systematic review.BMC women's health · 2025Pooled it
- Effects of Schistosoma haematobium infection and treatment on the systemic and mucosal immune phenotype, gene expression and microbiome: A systematic review.PLoS neglected tropical diseases · 2024Pooled it
- Correlates of prior HIV testing and schistosomiasis treatment: Baseline survey findings from the "creating demand for fishermen's schistosomiasis HIV services" (FISH) cluster-randomized trial in Mangochi, Malawi.PLoS neglected tropical diseases · 2023Trial
- Understanding the association between immune-modulating helminths and HPV or cervical cancer: A scoping review.PLoS neglected tropical diseases · 2026Article
- Microscopic detection and genetic characterization of schistosome eggs within cervicovaginal lavage sediments from cases of female genital schistosomiasis.Parasitology · 2025Article
- The impact of Schistosoma haematobium hybridization on molecular diagnosis of schistosomiasis: A review with emphasis on female genital schistosomiasis.PLoS neglected tropical diseases · 2025Review
- Sex as a biological variable in HIV-1 and schistosome co-infection.The lancet. HIV · 2025Review
- Knowledge, attitudes and practices toward female genital schistosomiasis among community women and healthcare professionals in Kimpese region, Democratic Republic of Congo.PLoS neglected tropical diseases · 2024Article
- Article
- Female genital schistosomiasis burden and risk factors in two endemic areas in Malawi nested in the Morbidity Operational Research for Bilharziasis Implementation Decisions (MORBID) cross-sectional study.PLoS neglected tropical diseases · 2024Article
- Visual diagnosis of female genital schistosomiasis in Zambian women from hand-held colposcopy: agreement of expert image review and association with clinical symptoms.Wellcome open research · 2023Article
- The Presence of Hemoglobin in Cervicovaginal Lavage Is Not Associated With Genital Schistosomiasis in Zambian Women From the BILHIV Study.Open forum infectious diseases · 2022Article
- The Road to Elimination: Current State of Schistosomiasis Research and Progress Towards the End Game.Frontiers in immunology · 2022Review
- Association of Female Genital Schistosomiasis With the Cervicovaginal Microbiota and Sexually Transmitted Infections in Zambian Women.Open forum infectious diseases · 2021Article
- BeyondAcademic pathologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 8 institutions in 7 countries.
Amy S SturtDepartment of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Emily L WebbMRC International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Catriona PattersonDepartment of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Comfort R PhiriZambart, Lusaka, Zambia.
Tobias MweeneZambart, Lusaka, Zambia.
Eyrun F KjetlandDepartment of Infectious Diseases, Oslo University Hospital, Oslo, Norway.
Maina MudendaDepartment of Obstetrics and Gynecology, Livingstone Central Hospital, Livingstone, Zambia.
Joyce MapaniDepartment of Obstetrics and Gynecology, Livingstone Central Hospital, Livingstone, Zambia.
Mable M MutengoInstitute of Basic and Biomedical Sciences, Levy Mwanawasa Medical University, Lusaka, Zambia.
James ChipetaDepartment of Pediatrics, University of Zambia, Lusaka, Zambia.
Govert J van DamDepartment of Parasitology, Leiden University Medical Center, Leiden, Netherlands.
Paul L A M CorstjensDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands.
Helen AylesDepartment of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Richard J HayesMRC International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Isaiah HansingoDepartment of Obstetrics and Gynecology, Livingstone Central Hospital, Livingstone, Zambia.
Piet CoolsFaculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Lisette van LieshoutDepartment of Parasitology, Leiden University Medical Center, Leiden, Netherlands.
Helena HelmbyDepartment of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Grace A McComseyUniversity Hospitals Cleveland Medical Center and Case Western Reserve University, Department of Pediatrics and Medicine, Cleveland, OH, United States.
Suzanna C FrancisMRC International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Amaya L BustinduyDepartment of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom.
London School of Hygiene & Tropical Medicine · GBLeiden University Medical Center · NLZambart · ZMCase Western Reserve University · USGhent University · BELusaka Apex Medical University · ZMUniversity of KwaZulu-Natal · ZAUniversity of Zambia · ZM
Funding
LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI Sinead Delany-Moretlwe, RAPHAEL J LANDOVITZ · 2011 to 2026
$779.5MSDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9MLC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2MMedical Research Council MR/K012126/1Medical Research Council MR/N023692/1Medical Research Council MR/R010161/1NIAID NIH HHS UM1 AI068613NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068619PEPFARWellcome Trust 205954/Z/17/Z
Abstract
HIV-1 infection disproportionately affects women in sub-Saharan Africa, where areas of high HIV-1 prevalence and
Indexed as
AnimalsAntigens, HelminthCervix UteriCross-Sectional StudiesCytokinesEndemic DiseasesFemaleGlycoproteinsHelminth ProteinsHIV-1HIV InfectionsHumansPrevalenceSchistosoma haematobiumSchistosomiasis haematobiaVaginaAntigens, Helminthcirculating anodic antigen, Schistosoma mansoniCytokinesGlycoproteinsHelminth Proteinscervicovaginal lavage (CVL)female genital schistosomiasisgenital tractHIV-1inflammationpolymerase chain reaction (PCR)S. haematobiumsub-Saharan Africa
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.