Evidence map›Paper›PMID 33737910›Full record

ArticleFrontiers in endocrinology2021

High Variability of Molecular Isoforms of AMH in Follicular Fluid and Granulosa Cells From Human Small Antral Follicles.

Linn Salto Mamsen, Jane Alrø Bøtkjær, Stine Gry Kristensen, Susanne Elisabeth Pors, Janni Vikkelsø Jeppesen, Ajay Kumar, Bhanu Kalra, Erik Ernst, Claus Yding Andersen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Study on the Function ofAnimals : an open access journal from MDPI · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Linn Salto MamsenLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children, and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Jane Alrø BøtkjærLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children, and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Stine Gry KristensenLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children, and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Susanne Elisabeth PorsLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children, and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Janni Vikkelsø JeppesenLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children, and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Ajay KumarAnsh Labs, LLC, Webster, TX, United States.
Bhanu KalraAnsh Labs, LLC, Webster, TX, United States.
Erik ErnstDepartment of Obstetrics and Gynaecology, Regional Hospital of Randers, Randers, Denmark.
Claus Yding AndersenLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children, and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Rigshospitalet · DKCopenhagen University Hospital · DKRegional Hospital Randers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-Müllerian hormone (AMH) is a member of the TGF-β superfamily produced by follicular granulosa cells (GCs) in women from late gestation to the end of reproductive life. AMH is thought to inhibit aromatase (i.e., CYP19) expression and decrease the conversion of androgens to oestrogens, especially in small antral follicles before dominance is achieved. Thus, AMH acts as a gatekeeper of ovarian steroidogenesis. However, the exact function and processing of AMH has not been fully elucidated. The present study measured and determined AMH isoforms in human follicular fluid (FF) from small antral follicles and in human GCs using four ELISAs, western blot, and immunofluorescence analysis. We evaluated the presence of the following isoforms: full-length AMH precursor (proAMH), cleaved associated AMH (AMH

Indexed as

AdolescentAdultAnti-Mullerian HormoneFemaleFollicular FluidGranulosa CellsHumansOvarian FollicleOvaryProtein IsoformsRetrospective StudiesYoung AdultAnti-Mullerian HormoneProtein IsoformsAMH isoformsanti müllerian hormoneendocrine functiongranulosa cells (GCs)human follicular fluid (HFF)

Identifiers

PMID33737910
PMCPMC7961079
OpenAlexW3134477733

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.